(Q36577507)

15 August 2017

1 reference

title

Mechanisms of Disease: the complement system and the pathogenesis of systemic lupus erythematosus (English)

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systemic lupus erythematosus

15 August 2017

main subject

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2

Marina Botto

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author name string

H Terence Cook

series ordinal

1

1 reference

15 August 2017

Marina Botto

series ordinal

2

1 reference

15 August 2017

publication date

1 June 2006

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Nature Clinical Practice Rheumatology

15 August 2017

published in

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15 August 2017

volume

2

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15 August 2017

issue

6

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15 August 2017

page(s)

330-337

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Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

Complement. First of two parts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Systemic exposure to irradiated apoptotic cells induces autoantibody production

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Links between complement abnormalities and systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Features of systemic lupus erythematosus in Dnase1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

A protective role for innate immunity in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Complement C4 is protective for lupus disease independent of C3

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Fc receptor-independent development of autoimmune glomerulonephritis in lupus-prone MRL/lpr mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Effects of complement factor D deficiency on the renal disease of MRL/lpr mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

No lupus nephritis in the absence of antiC1q autoantibodies?

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Anti-C1q autoantibodies in murine lupus nephritis

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Complement C3 activation is required for antiphospholipid antibody-induced fetal loss

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

TNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy loss

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Mannose-binding lectin variant alleles and the risk of arterial thrombosis in systemic lupus erythematosus.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Association of mannose-binding lectin gene variation with disease severity and infections in a population-based cohort of systemic lupus erythematosus patients.

1 reference

https://api.crossref.org/works/10.1038%2FNCPRHEUM0191

7 January 2021

Identifiers

DOI

10.1038/NCPRHEUM0191

1 reference

15 August 2017

1 reference