(Q36580244)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

José Manuel Calderón-Montaño

5 March 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Nicholas Valerie

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Thomas Lundbäck

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Emmanuele Crespan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Torkild Visnes

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Ann-Sofie Jemth

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Thomas Helleday

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Giovanni Maga

11

1 reference

ORCID Public Data File 2021

Sabin Llona-Minguez

1

Sabin Llona-Minguez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

2

Andreas Höglund

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

15

Pawel Baranczewski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

18

Elisee Wiita

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

19

Ingrid Almlöf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

21

Fredrik Jeppsson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Kristmundur Sigmundsson

22

Kristmundur Sigmundsson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Annika Jenmalm-Jensen

23

Annika Jenmalm Jensen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

24

Per Artursson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Ulrika Warpman Berglund

27

Ulrika Warpman Berglund

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

28

Martin Scobie

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Sylvain A Jacques

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Lars Johansson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Magnus Claesson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Olga Loseva

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Javier Piedrafita

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Laurent Meijer

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Estefanía Burgos Morón

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Ann-Louise Hagbjörk

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Richard Svensson

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

language of work or name

English

0 references

publication date

27 January 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medicinal Chemistry

5 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

1140-1148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation

5 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Comparative proteomics analysis of gastric cancer stem cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Triptolide directly inhibits dCTP pyrophosphatase.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Nitroaromatic compounds, from synthesis to biodegradation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Drug combination studies and their synergy quantification using the Chou-Talalay method

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Microwave-assisted parallel synthesis of fused heterocycles in a novel parallel multimode reactor.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Impact of cytosine 5-halogens on the interaction of DNA with restriction endonucleases and methyltransferase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Development of the proteasome inhibitor PS-341.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Bromination of deoxycytidine by eosinophil peroxidase: a mechanism for mutagenesis by oxidative damage of nucleotide precursors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Discovery of a potent, selective, and orally active proteasome inhibitor for the treatment of cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Boronic acids-a novel class of bacterial mutagen.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

A general solution for unstable boronic acids: slow-release cross-coupling from air-stable MIDA boronates.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753678

A new micromethod for the colorimetric determination of inorganic phosphate

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26771665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impact of enzyme concentration and residence time on apparent activity recovery in jump dilution analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26771665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26771665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACS.JMEDCHEM.5B01741

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26771665%20AND%20SRC:MED&resulttype=core&format=json