(Q36586167)

English

Effect of a Smac Mimetic (TL32711, Birinapant) on the Apoptotic Program and Apoptosis Biomarkers Examined with Validated Multiplex Immunoassays Fit for Clinical Use.

scientific article published on 7 October 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Effect of a Smac Mimetic (TL32711, Birinapant) on the Apoptotic Program and Apoptosis Biomarkers Examined with Validated Multiplex Immunoassays Fit for Clinical Use. (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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apoptotic process

0 references

Jeevan Prasaad Govindharajulu

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26446940%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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Apurva K Srivastava

1

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4 June 2020

Soumya Jaganathan

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26446940%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Laurie Stephen

3

1 reference

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4 June 2020

Melinda G Hollingshead

4

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4 June 2020

Adam Layhee

5

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4 June 2020

Eric Damour

6

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4 June 2020

Jennifer Donohue

8

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4 June 2020

Dominic Esposito

9

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4 June 2020

James P Mapes

10

1 reference

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4 June 2020

Robert J Kinders

11

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4 June 2020

Naoko Takebe

12

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4 June 2020

Joseph E Tomaszewski

13

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Europe PubMed Central

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4 June 2020

Shivaani Kummar

14

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Europe PubMed Central

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4 June 2020

James H Doroshow

15

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Europe PubMed Central

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4 June 2020

Ralph E Parchment

16

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Europe PubMed Central

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4 June 2020

language of work or name

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publication date

7 October 2015

1 reference

Europe PubMed Central

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15 August 2017

Clinical Cancer Research

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26446940%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

22

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Europe PubMed Central

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4 June 2020

4

1 reference

Europe PubMed Central

PMC publication ID

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4 June 2020

1000-1010

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26446940%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

9 September 2017

Molecular pathways: targeting inhibitor of apoptosis proteins in cancer--from molecular mechanism to therapeutic application

1 reference

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9 September 2017

Biomarker modulation following short-term vorinostat in women with newly diagnosed primary breast cancer

1 reference

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9 September 2017

Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models

1 reference

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9 September 2017

Biomarkers of cell death applicable to early clinical trials

1 reference

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9 September 2017

Targeting IAP proteins for therapeutic intervention in cancer

1 reference

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9 September 2017

Evaluation of pharmacodynamic biomarkers in a Phase 1a trial of dulanermin (rhApo2L/TRAIL) in patients with advanced tumours

1 reference

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9 September 2017

Hallmarks of Cancer: The Next Generation

1 reference

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Molecular biology of Bax and Bak activation and action

1 reference

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9 September 2017

Apoptosis and cancer: the genesis of a research field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

9 September 2017

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

9 September 2017

Biomarkers of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

9 September 2017

Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer: a review.

1 reference

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9 September 2017

Preclinical modeling of a phase 0 clinical trial: qualification of a pharmacodynamic assay of poly (ADP-ribose) polymerase in tumor biopsies of mouse xenografts

1 reference

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9 September 2017

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

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9 September 2017

Bim and the pro-survival Bcl-2 proteins: opposites attract, ERK repels

1 reference

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9 September 2017

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

9 September 2017

Bcl-2 family members: integrators of survival and death signals in physiology and pathology [corrected].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

9 September 2017

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

9 September 2017

Modulation of cell death by Bcl-XL through caspase interaction

1 reference

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9 September 2017

Intra- and inter-individual biological variability data bank

1 reference

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9 September 2017

Generation and application of data on biological variation in clinical chemistry

1 reference

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9 September 2017

Promotion of Caspase Activation by Caspase-9-mediated Feedback Amplification of Mitochondrial Damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

30 September 2017

The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

30 September 2017

The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

30 September 2017

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

30 September 2017

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4755826

30 September 2017

Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.

1 reference

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28 June 2018

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1 reference

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28 June 2018

Evasion of apoptosis as a cellular stress response in cancer

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28 June 2018

Apoptosis: Stabbed in the BAX.

1 reference

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YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts.

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Lamin B phosphorylation by protein kinase calpha and proteolysis during apoptosis in human leukemia HL60 cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/26446940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-14-3156

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26446940%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26446940%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26446940%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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