(Q42713862)

English

Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

apoptotic process

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inflammatory breast cancer

1 reference

based on heuristic

inferred from title

Herbert Kim Lyerly

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Jennifer L Allensworth

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Scott J Sauer

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Michael A Morse

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Gayathri R Devi

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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publication date

7 December 2012

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Breast Cancer Research and Treatment

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

137

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

359-371

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225169%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

https://scigraph.springernature.com/pub.10.1007/s10549-012-2352-6

0 references

Inflammatory breast cancer: the disease, the biology, the treatment

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

X-linked inhibitor of apoptosis protein inhibits apoptosis in inflammatory breast cancer cells with acquired resistance to an ErbB1/2 tyrosine kinase inhibitor

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Different gene expressions are associated with the different molecular subtypes of inflammatory breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Distinct molecular phenotype of inflammatory breast cancer compared to non-inflammatory breast cancer using Affymetrix-based genome-wide gene-expression analysis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Acquired resistance to small molecule ErbB2 tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Prognostic value of the X-linked inhibitor of apoptosis protein for invasive ductal breast cancer with triple-negative phenotype

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

The inhibitors of apoptosis: there is more to life than Bcl2.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

The inhibitor of apoptosis protein family (IAPs): an emerging therapeutic target in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Targeting XIAP for the treatment of malignancy

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

X-linked Inhibitor of Apoptosis: A Chemoresistance Factor or a Hollow Promise

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Targeting IAP proteins for therapeutic intervention in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

XIAP impairs Smac release from the mitochondria during apoptosis.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

SM-164: a novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Proinflammatory characteristics of SMAC/DIABLO-induced cell death in antitumor therapy.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Smac mimetics and TNFalpha: a dangerous liaison?

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Constitutively activated nuclear factor-kappaB, but not induced NF-kappaB, leads to TRAIL resistance by up-regulation of X-linked inhibitor of apoptosis protein in human cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Smac mimetic enables the anticancer action of BCG-stimulated neutrophils through TNF-α but not through TRAIL and FasL.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Attenuating Smac mimetic compound 3-induced NF-kappaB activation by luteolin leads to synergistic cytotoxicity in cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death, and induction of FLIP by NF-κB is required to prevent it.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Requirement of nuclear factor κB for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-induced apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2352-6

21 January 2018

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