(Q36598930)

English

Cross-linking mass spectrometry and mutagenesis confirm the functional importance of surface interactions between CYP3A4 and holo/apo cytochrome b(5).

scientific article published on 14 November 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Cross-linking mass spectrometry and mutagenesis confirm the functional importance of surface interactions between CYP3A4 and holo/apo cytochrome b(5). (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

David R Goodlett

7

object named as

David R Goodlett

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Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Chunsheng Zhao

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Qiuxia Gao

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Arthur G Roberts

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Scott A Shaffer

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Catalin E Doneanu

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Song Xue

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Sidney D Nelson

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

William M Atkins

9

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Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

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publication date

14 November 2012

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Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

51

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Europe PubMed Central

PMC publication ID

15 August 2017

47

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

9488-9500

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Allosteric activation of cytochrome P450 3A4 by α-naphthoflavone: branch point regulation revealed by isotope dilution analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Accelerating protein docking in ZDOCK using an advanced 3D convolution library

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Membrane position of ibuprofen agrees with suggested access path entrance to cytochrome P450 2C9 active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

The interaction of microsomal cytochrome P450 2B4 with its redox partners, cytochrome P450 reductase and cytochrome b(5).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Characterization of protein cross-links via mass spectrometry and an open-modification search strategy.

1 reference

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30 September 2017

The collaboratory for MS3D: a new cyberinfrastructure for the structural elucidation of biological macromolecules and their assemblies using mass spectrometry-based approaches

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30 September 2017

CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis

1 reference

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30 September 2017

Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

The ins and outs of cytochrome P450s.

1 reference

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30 September 2017

Identification of the interactions between cytochrome P450 2E1 and cytochrome b5 by mass spectrometry and site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Human cytochrome b5 requires residues E48 and E49 to stimulate the 17,20-lyase activity of cytochrome P450c17.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

GROMACS: fast, flexible, and free

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Role of cytochrome b5 in catalysis by cytochrome P450 2B4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Fluorescent photoaffinity labeling of cytochrome P450 3A4 by lapachenole: identification of modification sites by mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Functional interaction of cytochrome P450 with its redox partners: a critical assessment and update of the topology of predicted contact regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

The many roles of cytochrome b5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

The roles of cytochrome b5 in cytochrome P450 reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

The importance of SRS-1 residues in catalytic specificity of human cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Solution structure of oxidized microsomal rabbit cytochrome b5. Factors determining the heterogeneous binding of the heme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Interactions between cytochrome P450 and cytochrome b5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Origin of the photoacoustic signal in cytochrome P-450cam: role of the Arg186-Asp251-Lys178 bifurcated salt bridge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Structural properties of apocytochrome b5: presence of a stable native core

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

30 September 2017

CYP2C9 amino acid residues influencing phenytoin turnover and metabolite regio- and stereochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

28 June 2018

Comparison of the complexes formed by cytochrome P450cam with cytochrome b5 and putidaredoxin, two effectors of camphor hydroxylase activity

1 reference

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28 June 2018

X-ray structure of the cupredoxin amicyanin, from Paracoccus denitrificans, refined at 1.31 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

28 June 2018

Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

28 June 2018

Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

28 June 2018

Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

28 June 2018

Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

28 June 2018

NADPH-cytochrome P-450 oxidoreductase. The role of cysteine 566 in catalysis and cofactor binding.

1 reference

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28 June 2018

Mapping electrostatic interactions in macromolecular associations

1 reference

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28 June 2018

Dynamic structures of adrenocortical cytochrome P-450 in proteoliposomes and microsomes: protein rotation study

1 reference

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28 June 2018

Kinetics of electron transfer between NADPH-cytochrome P450 reductase and cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Flexibility of human cytochrome P450 enzymes: molecular dynamics and spectroscopy reveal important function-related variations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Catalytic turnover of pyrene by CYP3A4: evidence that cytochrome b5 directly induces positive cooperativity

1 reference

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20 September 2018

The thermodynamic landscape of testosterone binding to cytochrome P450 3A4: ligand binding and spin state equilibria

1 reference

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20 September 2018

Refinement and structural analysis of bovine cytochrome b5 at 1.5 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

The role of the length and sequence of the linker domain of cytochrome b5 in stimulating cytochrome P450 2B4 catalysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Topological changes in the CYP3A4 active site probed with phenyldiazene: effect of interaction with NADPH-cytochrome P450 reductase and cytochrome b5 and of site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Stimulation of cytochrome P450 reactions by apo-cytochrome b5: evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5 or heme oxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Interaction of apo-cytochrome b5 with cytochromes P4503A4 and P45017A: relevance of heme transfer reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

The stoichiometry of the cytochrome P-450-catalyzed metabolism of methoxyflurane and benzphetamine in the presence and absence of cytochrome b5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568533

20 September 2018

Dynamics and Hydration of the Active Sites of Mammalian Cytochromes P450 Probed by Molecular Dynamics Simulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different requirement for cytochrome b5 in NADPH-supported O-deethylation of p-nitrophenetole catalyzed by two types of microsomal cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome b5 increases the rate of product formation by cytochrome P450 2B4 and competes with cytochrome P450 reductase for a binding site on cytochrome P450 2B4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of an independent structural unit in apocytochrome b5

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zero-length crosslinking procedure with the use of active esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence for electron transfer from ferrous cytochrome b5 to the oxyferrous intermediate of liver microsomal cytochrome P-450 LM2

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of binary complex formations between cytochrome P-450, cytochrome b5, and NADPH-cytochrome P-450 reductase of hepatic microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triazolam substrate inhibition: evidence of competition for heme-bound reactive oxygen within the CYP3A4 active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the participation of cytochrome b 5 in hepatic microsomal mixed-function oxidation reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome b5 inhibits electron transfer from NADPH-cytochrome P450 reductase to ferric cytochrome P450 2B4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The high-level expression in Escherichia coli of the membrane-bound form of human and rat cytochrome b5 and studies on their mechanism of function

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apo-cytochrome b5 as an indicator of changes in heme accessability: preliminary studies with cytochrome P450 3A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of ionic strength on the P450 monooxygenase reaction and role of cytochrome b5 in the process

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxylation of prostaglandins by inducible isozymes of rabbit liver microsomal cytochrome P-450. Participation of cytochrome b5

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similarities in structure between holocytochrome b5 and apocytochrome b5: NMR studies of the histidine residues

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cytochrome b5 on cytochrome P-450-catalyzed reactions. Studies with manganese-substituted cytochrome b5

1 reference

https://pubmed.ncbi.nlm.nih.gov/23150942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI301069R

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

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