(Q36600942)

English

Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia

scientific article published on 21 September 2006

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia (English)

1 reference

Europe PubMed Central

15 August 2017

author name string

Pedersen-Bjergaard J

1

1 reference

Europe PubMed Central

15 August 2017

Christiansen DH

2

1 reference

Europe PubMed Central

15 August 2017

Desta F

3

1 reference

Europe PubMed Central

15 August 2017

Andersen MK

4

1 reference

Europe PubMed Central

15 August 2017

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21 September 2006

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Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

20

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Europe PubMed Central

15 August 2017

1943-1949

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Europe PubMed Central

15 August 2017

11

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Europe PubMed Central

15 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404381

0 references

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

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Pooled analysis of clinical and cytogenetic features in treatment-related and de novo adult acute myeloid leukemia and myelodysplastic syndromes based on a consecutive series of 761 patients analyzed 1976-1993 and on 5098 unselected cases reported i

1 reference

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21 January 2018

Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.

1 reference

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21 January 2018

Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia

1 reference

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21 January 2018

Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML.

1 reference

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21 January 2018

Genetics of myeloid leukemias

1 reference

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21 January 2018

Mutations of AML1 are common in therapy-related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation

1 reference

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21 January 2018

Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia

1 reference

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21 January 2018

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

1 reference

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21 January 2018

Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

1 reference

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21 January 2018

Secondary acute myeloid leukemia in children treated for acute lymphoid leukemia

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21 January 2018

11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: report from an international workshop

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21 January 2018

Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes

1 reference

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21 January 2018

Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia

1 reference

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21 January 2018

RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years

1 reference

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21 January 2018

Therapy-related acute myeloid leukemia with t(8;21), inv(16), and t(8;16): a report on 25 cases and review of the literature

1 reference

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21 January 2018

21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: report from an international workshop

1 reference

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21 January 2018

DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

1 reference

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The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

1 reference

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21 January 2018

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

1 reference

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21 January 2018

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

1 reference

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21 January 2018

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

1 reference

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21 January 2018

A gain-of-function mutation of JAK2 in myeloproliferative disorders

1 reference

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21 January 2018

The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes

1 reference

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21 January 2018

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

1 reference

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21 January 2018

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

21 January 2018

DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

21 January 2018

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

1 reference

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21 January 2018

FLT3 and MLL intragenic abnormalities in AML reflect a common category of genotoxic stress.

1 reference

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21 January 2018

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

1 reference

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21 January 2018

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

1 reference

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21 January 2018

Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia

1 reference

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21 January 2018

FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

1 reference

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21 January 2018

Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

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Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

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inferred from DOI database lookup

Activating mutations of JAK2V617F are uncommon in t-MDS and t-AML and are only observed in atypic cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

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Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia

1 reference

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7 January 2021

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Centromeric breakage and highly rearranged chromosome derivatives associated with mutations of TP53 are common in therapy-related MDS and AML after therapy with alkylating agents: an M-FISH study

1 reference

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7 January 2021

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Duplication or amplification of chromosome band 11q23, including the unrearranged MLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of the TP53 gene and to previous therapy with alkylating agents

1 reference

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7 January 2021

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inferred from DOI database lookup

Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML

1 reference

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7 January 2021

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Secondary acute leukemia and myelodysplastic syndrome with 11q23 abnormalities. EU Concerted Action 11q23 Workshop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

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Balanced chromosome aberrations in leukemias following chemotherapy with DNA-topoisomerase II inhibitors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia

1 reference

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7 January 2021

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Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

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inferred from DOI database lookup

Therapy-related acute promyelocytic leukemia: a report on 16 cases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Increase therapy-related leukemia secondary to breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Insights into leukemogenesis from therapy-related leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Potential role for DNA topoisomerase II poisons in the generation of t(11;20)(p15;q11) translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404381

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2404381

1 reference

Europe PubMed Central

15 August 2017

release_lc4efralxzgz7ijtj2jysvvaay

1 reference

https://api.fatcat.wiki/v0/release/lc4efralxzgz7ijtj2jysvvaay

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

15 August 2017

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