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Signaling networks in human pluripotent stem cells
scientific article published on 22 October 2012
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
title
Signaling networks in human pluripotent stem cells
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
main subject
pluripotency
1 reference
based on heuristic
inferred from title
author name string
Stephen Dalton
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
publication date
22 October 2012
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
published in
Current Opinion in Cell Biology
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
volume
25
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
issue
2
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
page(s)
241-246
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
cites work
Reconciling the different roles of Gsk3β in "naïve" and "primed" pluripotent stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Accessing naïve human pluripotency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Protein kinase C mediated extraembryonic endoderm differentiation of human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Maintaining embryonic stem cell pluripotency with Wnt signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Chemically defined conditions for human iPSC derivation and culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Self-renewal versus lineage commitment of embryonic stem cells: protein kinase C signaling shifts the balance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Pluripotency factors regulate definitive endoderm specification through eomesodermin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
The role of FGF/Erk signaling in pluripotent cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
The ground state of pluripotency.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3beta signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Molecular and biological properties of pluripotent embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Feeder-independent culture of human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Basic fibroblast growth factor support of human embryonic stem cell self-renewal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Feeder-free growth of undifferentiated human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
Embryonic stem cell lines derived from human blastocysts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
30 September 2017
A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
28 June 2018
FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
28 June 2018
Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
Wnt: what's needed to maintain pluripotency?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
Inhibition of ERK1/2 prevents neural and mesendodermal differentiation and promotes human embryonic stem cell self-renewal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570582
retrieved
20 September 2018
Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23092754
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CEB.2012.09.005
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
PMCID
3570582
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
PubMed ID
23092754
1 reference
stated in
Europe PubMed Central
PMCID
3570582
retrieved
15 August 2017
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