(Q36604951)

15 August 2017

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title

Renal Toll-like receptors: recent advances and implications for disease (English)

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15 August 2017

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Tarek M El-Achkar

1

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15 August 2017

Pierre C Dagher

series ordinal

2

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15 August 2017

publication date

1 October 2006

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Nature Clinical Practice Nephrology

15 August 2017

published in

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15 August 2017

volume

2

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15 August 2017

issue

10

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15 August 2017

page(s)

568-581

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Innate immune sensing and its roots: the story of endotoxin

15 August 2017

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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The interface between innate and adaptive immunity

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Toll-like receptor ligands directly promote activated CD4+ T cell survival

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Control of B-cell responses by Toll-like receptors

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Endogenous ligands of Toll-like receptors

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An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells

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HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

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Toll-like receptors, endogenous ligands, and systemic autoimmune disease.

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Imiquimod: in superficial basal cell carcinoma

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Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines.

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Toll-like receptors: function and roles in lung disease

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In Vivo Expression of Proinflammatory Mediators in the Adult Heart after Endotoxin Administration: The Role of Toll‐Like Receptor–4

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7 January 2021

Endotoxin and cytokine regulation of toll-like receptor (TLR) 2 and TLR4 gene expression in murine liver and hepatocytes

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7 January 2021

Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

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7 January 2021

In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation

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7 January 2021

Role of Toll-like receptor 4 in endotoxin-induced acute renal failure

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7 January 2021

Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation.

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Minireview: functions of the renal tract epithelium in coordinating the innate immune response to infection.

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Signaling danger: toll-like receptors and their potential roles in kidney disease

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Leucine-rich repeats and pathogen recognition in Toll-like receptors.

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MyD88, an adapter protein involved in interleukin-1 signaling

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7 January 2021

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

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7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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7 January 2021

Map kinase signaling pathways and hematologic malignancies

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7 January 2021

The biology of p38 kinase: a central role in inflammation

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7 January 2021

MAPK signal pathways in the regulation of cell proliferation in mammalian cells

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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7 January 2021

Toll-like receptor signaling

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7 January 2021

Myeloid differentiation factor 88-dependent and -independent pathways in toll-like receptor signaling

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7 January 2021

Effects of microinjection of synthetic Bcl-2 domain peptides on apoptosis of renal tubular epithelial cells.

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7 January 2021

Apoptosis in sepsis: a new target for therapeutic exploration

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7 January 2021

Acute renal failure in endotoxemia is dependent on caspase activation

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7 January 2021

Apoptosis and NF-kappa B: the FADD connection

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7 January 2021

Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

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7 January 2021

The apoptotic signaling pathway activated by Toll-like receptor-2

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7 January 2021

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Tissue-specific mRNA expression profiles of human toll-like receptors and related genes

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells

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7 January 2021

Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells

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7 January 2021

Novel Role of Toll-Like Receptor 3 in Hepatitis C-Associated Glomerulonephritis

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7 January 2021

Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors.

1 reference

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7 January 2021

Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice

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7 January 2021

Toll-like receptor-7 modulates immune complex glomerulonephritis

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7 January 2021

A toll-like receptor that prevents infection by uropathogenic bacteria

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7 January 2021

Ischemia-reperfusion injury activates innate immunity in rat kidneys

1 reference

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7 January 2021

Cyclosporine-induced renal injury induces toll-like receptor and maturation of dendritic cells.

1 reference

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7 January 2021

Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa

1 reference

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7 January 2021

Developmental aspects of Escherichia coli-induced innate responses in rat renal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Sepsis induces changes in the expression and distribution of Toll-like receptor 4 in the rat kidney.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

1 reference

7 January 2021

The pathophysiology and treatment of sepsis

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https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

The immunopathogenesis of sepsis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Genetic Control of Leucocyte Responses to Endotoxin

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Mouse genetic locus Lps influences susceptibility to Neisseria meningitidis infection

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Acute renal failure and sepsis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

The pathogenesis of septic acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Ischemic proximal tubular injury primes mice to endotoxin-induced TNF-alpha generation and systemic release

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

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7 January 2021

Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide

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7 January 2021

Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.

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7 January 2021

Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide

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7 January 2021

TLR4 is the signaling but not the lipopolysaccharide uptake receptor

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Toll-like receptor and heme oxygenase-1 signaling in hepatic ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Toll-like receptor 4 mediates ischemia/reperfusion injury of the heart

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7 January 2021

Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction.

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7 January 2021

Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

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7 January 2021

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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7 January 2021

Neutrophil recruitment and resistance to urinary tract infection.

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7 January 2021

Toll-like receptor signaling and chemokine receptor expression influence the severity of urinary tract infection

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli

1 reference

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7 January 2021

Toll-like receptor-4: renal cells and bone marrow cells signal for neutrophil recruitment during pyelonephritis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Type 1 fimbriae deliver an LPS- and TLR4-dependent activation signal to CD14-negative cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Escherichia coli P fimbriae utilize the Toll-like receptor 4 pathway for cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14.

1 reference

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7 January 2021

Tamm-Horsfall glycoprotein: biology and clinical relevance

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E. coli from binding to uroplakin Ia and Ib receptors

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication

1 reference

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7 January 2021

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Heat shock proteins, anti-heat shock protein reactivity and allograft rejection.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

TH1 immune responses to fully MHC mismatched allografts are diminished in the absence of MyD88, a toll-like receptor signal adaptor protein

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

1 reference

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7 January 2021

Relevance of Toll-like receptor-4 polymorphisms in renal transplantation.

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7 January 2021

Cell biology of the glomerular podocyte

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7 January 2021

Induction of B7-1 in podocytes is associated with nephrotic syndrome

1 reference

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7 January 2021

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Effect of meningococcal endotoxin on the immune response

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

A Toll-like receptor recognizes bacterial DNA

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus

1 reference

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7 January 2021

Toll-like receptor 9 signaling protects against murine lupus

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7 January 2021

Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.

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7 January 2021

Association study of Toll-like receptor 9 gene polymorphism in Korean patients with systemic lupus erythematosus.

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7 January 2021

Polymorphisms of toll-like receptor 2 and 4 genes in rheumatoid arthritis and systemic lupus erythematosus.

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7 January 2021

G-rich DNA suppresses systemic lupus.

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7 January 2021

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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7 January 2021

Spliceosomal UsnRNP biogenesis, structure and function

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7 January 2021

A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus

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7 January 2021

Immunotherapeutic uses of CpG oligodeoxynucleotides

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https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Therapeutics targeting the innate immune system

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7 January 2021

Toll-like receptor therapies compete to reduce side effects

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7 January 2021

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

1 reference

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7 January 2021

Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

The extra domain A of fibronectin activates Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Discrimination of bacterial lipoproteins by Toll-like receptor 6

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0300

7 January 2021

Identifiers

DOI

10.1038/NCPNEPH0300

1 reference

15 August 2017

1 reference