(Q36606886)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

review article

1 reference

title

Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

3

Michael Trauner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1

Andreas Geier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

language of work or name

English

0 references

publication date

1 October 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Gastroenterology & Hepatology

20 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

574-585

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

20 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Therapeutic approaches to innate immunity: severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Hepatic response to sepsis: interaction between coagulation and inflammatory processes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Inflammation-induced cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

The epidemiology of sepsis in the United States from 1979 through 2000

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

The causes of obvious jaundice in South West Wales: perceptions versus reality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Molecular pathogenesis of cholestasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Sclerosing cholangitis following severe trauma: description of a remarkable disease entity with emphasis on possible pathophysiologic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Progressive sclerosing cholangitis after septic shock: a new variant of vanishing bile duct disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Bile salt transporters: molecular characterization, function, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Functional Complementation between a Novel Mammalian Polygenic Transport Complex and an Evolutionarily Ancient Organic Solute Transporter, OSTα-OSTβ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Pathophysiology of cholangiopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Nuclear receptor regulation of hepatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Molecular aspects of bile formation and cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Molecular regulation of hepatocellular transport systems in cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

The cholangiopathies: disorders of biliary epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Effect of Induced Fever on Sulfobromophthalein Kinetics in Man

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Tumour necrosis factor, cholestatic jaundice, and chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

The hepatic microvascular responses to sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Sepsis and cholestasis: basic findings in the sinusoid and bile canaliculus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Bench-to-bedside review: microvascular dysfunction in sepsis--hemodynamics, oxygen transport, and nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

The syndrome of disappearing intrahepatic bile ducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Multiple factors regulate the rat liver basolateral sodium-dependent bile acid cotransporter gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Molecular alterations in hepatocyte transport mechanisms in acquired cholestatic liver disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Short-term regulation of canalicular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Increased iNOS activity is essential for hepatic epithelial tight junction dysfunction in endotoxemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Interruption of hepatic gap junctional communication in the rat during inflammation induced by bacterial lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Regulation of hepatic connexins in cholestasis: possible involvement of Kupffer cells and inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Proinflammatory cytokines inhibit secretion in rat bile duct epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

21 January 2018

Cholestatic syndromes

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Clinical significance and pathogenesis of hyperbilirubinemia associated with Staphylococcus aureus septicemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Secondary sclerosing cholangitis: a comparison to primary sclerosing cholangitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Gastrointestinal disorders of the critically ill. Shock liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Ischemic hepatitis: clinical presentation and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Hypoxic hepatitis: clinical and hemodynamic study in 142 consecutive cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Early goal-directed therapy in the treatment of severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Antimicrobial therapy for patients with severe sepsis and septic shock: an evidence-based review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

ABC of oral bioavailability: transporters as gatekeepers in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Review article: mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Use of corticosteroid therapy in patients with sepsis and septic shock: an evidence-based review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Emerging indications for albumin dialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

Sepsis-associated cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Sepsis and cholestasis

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Endotoxin-induced cytokine gene expression and excretion in the liver

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Interleukin-1 receptor type I gene-deficient bile duct-ligated mice are partially protected against endotoxin

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

When bile ducts say NO: the good, the bad, and the ugly

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Nitric oxide blocks bile canalicular contraction by inhibiting inositol trisphosphate-dependent calcium mobilization

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Interleukin-1beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Early events in sepsis-associated cholestasis

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Sclerosing cholangitis and liver cirrhosis after extrabiliary infections: report on three cases

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Bile ductular cholestasis: an ominous histopathologic sign related to sepsis and "cholangitis lenta"

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

Ischemic hepatitis: clinical features, diagnosis and prognosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

7 January 2021

https://api.crossref.org/works/10.1038%2FNCPGASTHEP0602

1 reference

7 January 2021

Identifiers

DOI

10.1038/NCPGASTHEP0602

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17008927%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference