(Q36607050)

English

Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy.

scientific article published on 19 December 2012

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21 February 2020

Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy (English)

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21 February 2020

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human papilloma virus

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object named as

human papillomavirus

29 September 2024

based on heuristic

inferred from title

Michelle A Ozbun

4

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21 February 2020

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Zurab Surviladze

1

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21 February 2020

Rosa T Sterk

2

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21 February 2020

Sergio A DeHaro

3

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21 February 2020

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19 December 2012

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21 February 2020

Journal of Virology

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21 February 2020

87

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21 February 2020

5

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21 February 2020

2508-2517

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21 February 2020

Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes

1 reference

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30 September 2017

Entry of human papillomavirus type 16 by actin-dependent, clathrin- and lipid raft-independent endocytosis

1 reference

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The mTOR signalling pathway in human cancer

1 reference

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Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections.

1 reference

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Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance.

1 reference

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The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1

1 reference

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Manipulation or capitulation: virus interactions with autophagy

1 reference

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mTORC1 signaling: what we still don't know

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The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis

1 reference

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30 September 2017

Usage of heparan sulfate, integrins, and FAK in HPV16 infection

1 reference

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Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase

1 reference

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30 September 2017

mTOR regulation of autophagy

1 reference

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30 September 2017

Autophagy, Immunity, and Microbial Adaptations

1 reference

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30 September 2017

Molecular mechanisms of mTOR-mediated translational control

1 reference

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30 September 2017

Autophagy, antiviral immunity, and viral countermeasures

1 reference

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30 September 2017

Establishment of human papillomavirus infection requires cell cycle progression

1 reference

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30 September 2017

Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes

1 reference

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30 September 2017

Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy

1 reference

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30 September 2017

PI3K-Akt signaling and viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Clathrin- and caveolin-independent entry of human papillomavirus type 16--involvement of tetraspanin-enriched microdomains (TEMs)

1 reference

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30 September 2017

Virus activated filopodia promote human papillomavirus type 31 uptake from the extracellular matrix

1 reference

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Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11

1 reference

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30 September 2017

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

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CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization

1 reference

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30 September 2017

c-Src trafficking and co-localization with the EGF receptor promotes EGF ligand-independent EGF receptor activation and signaling

1 reference

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30 September 2017

The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Mechanisms of human papillomavirus type 16 neutralization by l2 cross-neutralizing and l1 type-specific antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

FoxO3 controls autophagy in skeletal muscle in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Defining the role of mTOR in cancer

1 reference

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30 September 2017

AKT/PKB signaling: navigating downstream

1 reference

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30 September 2017

Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs

1 reference

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30 September 2017

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Papillomavirus virus-like particles activate the PI3-kinase pathway via alpha-6 beta-4 integrin upon binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Virus entry: open sesame

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

TOR signaling in growth and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

mTOR signaling: implications for cancer and anticancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Human papillomaviruses bind a basal extracellular matrix component secreted by keratinocytes which is distinct from a membrane-associated receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Growing roles for the mTOR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

1 reference

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30 September 2017

Upstream and downstream of mTOR

1 reference

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30 September 2017

The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival

1 reference

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30 September 2017

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

1 reference

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30 September 2017

Different heparan sulfate proteoglycans serve as cellular receptors for human papillomaviruses

1 reference

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30 September 2017

Hierarchical phosphorylation of the translation inhibitor 4E-BP1

1 reference

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EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion

1 reference

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30 September 2017

The target of rapamycin (TOR) proteins

1 reference

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1 reference

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30 September 2017

Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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Phosphorylation of the PTEN tail regulates protein stability and function

1 reference

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1 reference

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30 September 2017

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

1 reference

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The L1 major capsid protein of human papillomavirus type 11 recombinant virus-like particles interacts with heparin and cell-surface glycosaminoglycans on human keratinocytes

1 reference

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30 September 2017

The human papillomavirus type 16 E5-protein modulates ligand-dependent activation of the EGF receptor family in the human epithelial cell line HaCaT.

1 reference

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30 September 2017

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

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30 September 2017

Role of translocation in the activation and function of protein kinase B

1 reference

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30 September 2017

Identification of the alpha6 integrin as a candidate receptor for papillomaviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

30 September 2017

Autophagy and Akt promote survival in glioma

1 reference

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28 June 2018

Autophagy induction by the pathogen receptor CD46.

1 reference

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28 June 2018

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1 reference

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28 June 2018

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors

1 reference

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28 June 2018

Increased levels and constitutive tyrosine phosphorylation of the epidermal growth factor receptor contribute to autonomous growth of human papillomavirus type 16 immortalized human keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3571372

28 June 2018

3-Methyladenine, an inhibitor of autophagy, has multiple effects on metabolism

1 reference

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28 June 2018

Ca2(+)-dependent binding of tamoxifen to calmodulin isolated from bovine brain

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28 June 2018

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1 reference

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20 September 2018

PKR-dependent autophagic degradation of herpes simplex virus type 1.

1 reference

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20 September 2018

Src kinases regulate PKB activation and modulate cytokine and chemoattractant-controlled neutrophil functioning.

1 reference

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20 September 2018

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

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20 September 2018

Human Papillomavirus Type 16 E7 Up-regulates AKT Activity through the Retinoblastoma Protein

1 reference

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4 December 2018

Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/23255786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23255786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of inhibition of lipid peroxidation by tamoxifen and 4-hydroxytamoxifen introduced into liposomes. Similarity to cholesterol and ergosterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23255786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.02319-12

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23255786%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23255786%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23255786%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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