(Q36611637)

15 August 2017

A novel self-microemulsifying formulation of paclitaxel for oral administration to patients with advanced cancer (English)

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15 August 2017

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10

J H Beijnen

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15 August 2017

S A Veltkamp

1

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15 August 2017

B Thijssen

2

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15 August 2017

J S Garrigue

3

1 reference

15 August 2017

G Lambert

4

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15 August 2017

F Lallemand

5

1 reference

15 August 2017

F Binlich

6

1 reference

15 August 2017

A D R Huitema

7

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15 August 2017

B Nuijen

8

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15 August 2017

A Nol

9

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15 August 2017

J H M Schellens

11

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15 August 2017

language of work or name

English

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publication date

22 August 2006

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British Journal of Cancer

15 August 2017

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15 August 2017

95

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15 August 2017

6

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15 August 2017

729-734

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6603312

15 August 2017

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cites work

A simple and sensitive assay for the quantitative analysis of paclitaxel and metabolites in human plasma using liquid chromatography/tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Excipient effects on in vitro cytotoxicity of a novel paclitaxel self‐emulsifying drug delivery system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

30 September 2017

Oral delivery of taxanes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Role of formulation vehicles in taxane pharmacology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Pharmacokinetic modeling of paclitaxel encapsulation in Cremophor EL micelles

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Population pharmacokinetics of orally administered paclitaxel formulated in Cremophor EL

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Pharmacokinetics of oral cyclosporin A when co-administered to enhance the oral absorption of paclitaxel

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

The effect of different doses of cyclosporin A on the systemic exposure of orally administered paclitaxel

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360510

Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans

20 September 2018

1 reference

12 December 2020

High-performance liquid chromatographic procedures for the quantitative determination of paclitaxel (Taxol) in human urine

1 reference

12 December 2020

Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL

1 reference

12 December 2020

Pharmacokinetics of paclitaxel and carboplatin in a dose-escalating and dose-sequencing study in patients with non-small-cell lung cancer. The European Cancer Centre

1 reference

12 December 2020

Plasma concentrations of polysorbate 80 measured in patients following administration of docetaxel or etoposide

1 reference

12 December 2020

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A

1 reference

12 December 2020

Coadministration of oral cyclosporin A enables oral therapy with paclitaxel

1 reference

12 December 2020

Phase I and pharmacokinetic study of oral paclitaxel

1 reference

12 December 2020

Metabolism and excretion of paclitaxel after oral administration in combination with cyclosporin A and after i.v. administration

1 reference

12 December 2020

Use of water-soluble liquid vitamin E to enhance cyclosporine absorption in children after liver transplant

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6603312

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15 August 2017

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15 August 2017

PubMed publication ID

16926835

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