(Q36614674)

English

Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2alpha may signal skeletal muscle atrophy in weight-losing cancer patients

scientific article published on 18 December 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2alpha may signal skeletal muscle atrophy in weight-losing cancer patients (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

phosphorylation

0 references

author name string

H L Eley

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

R J E Skipworth

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

D A C Deans

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

K C H Fearon

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

M J Tisdale

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

0 references

publication date

18 December 2007

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

British Journal of Cancer

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

98

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

443-449

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6604150

0 references

Attenuation of muscle atrophy in a murine model of cachexia by inhibition of the dsRNA-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Mechanism of induction of muscle protein degradation by angiotensin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Cancer cachexia is regulated by selective targeting of skeletal muscle gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Induction of apoptosis by a cachectic-factor in murine myotubes and inhibition by eicosapentaenoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Phosphorylation of the RNA-dependent protein kinase regulates its RNA-binding activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Induction of muscle protein degradation by a tumour factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Induction of cachexia in mice by a product isolated from the urine of cachectic cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

The eIF-2alpha kinases and the control of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

The guanine nucleotide-exchange factor, eIF-2B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

30 September 2017

PKR--a protein kinase regulated by double-stranded RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

28 June 2018

Protein synthesis in muscle measured in vivo in cachectic patients with cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

28 June 2018

Fasting plasma amino acid levels in cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

28 June 2018

Contribution of elevated protein turnover and anorexia to cachexia in patients with hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

28 June 2018

Apoptosis is present in skeletal muscle of cachectic gastro-intestinal cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

20 September 2018

Increased expression of proteasome subunits in skeletal muscle of cancer patients with weight loss.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

20 September 2018

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

20 September 2018

Inhibition of protein synthesis in apoptosis: differential requirements by the tumor necrosis factor alpha family and a DNA-damaging agent for caspases and the double-stranded RNA-dependent protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

20 September 2018

Expression of apoptosis regulatory proteins in the skeletal muscle of tumor-bearing rabbits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361431

20 September 2018

Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18087277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR

1 reference

https://pubmed.ncbi.nlm.nih.gov/18087277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of the inhibition of protein synthesis by vasopressin in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/18087277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of IL-1 induced inhibition of protein synthesis in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/18087277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II directly inhibits protein synthesis in murine myotubes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18087277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skeletal muscle atrophy, a link between depression of protein synthesis and increase in degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18087277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA Fragmentation Occurs in Skeletal Muscle during Tumor Growth: A Link with Cancer Cachexia?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18087277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJC.6604150

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

0 references

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