(Q36615898)

15 August 2017

Novel loci and pathways significantly associated with longevity (English)

1 reference

15 August 2017

3

Junxia Min

1 reference

15 August 2017

Marianne Nygaard

42

0 references

Mingbang Wang

Mingbang Wang

8

0 references

Michael W. Lutz

Michael W Lutz

46

0 references

Tom Perls

Thomas Perls

49

0 references

Paola Sebastiani

Paola Sebastiani

50

0 references

Qihua Tan

Qihua Tan

48

0 references

Kaare Christensen

Kaare Christensen

44

0 references

Yang Huanming

56

Huanming Yang

1 reference

15 August 2017

31

Lars Bolund

1 reference

15 August 2017

45

Claudio Franceschi

1 reference

15 August 2017

57

James W Vaupel

1 reference

15 August 2017

52

Eline Slagboom

1 reference

15 August 2017

2

Chao Nie

1 reference

15 August 2017

6

Huashuai Chen

1 reference

15 August 2017

32

Anatoliy Yashin

1 reference

15 August 2017

51

Joris Deelen

1 reference

15 August 2017

53

Elizabeth Hauser

1 reference

15 August 2017

Xiaomin Liu

4

0 references

William Gottschalk

William Gottschalk

36

0 references

Xiao Liu

Xiao Liu

21

0 references

Xun Xu

Xun Xu

40

0 references

author name string

Yi Zeng

1

1 reference

15 August 2017

Mengmeng Li

5

1 reference

15 August 2017

Hanshi Xu

7

1 reference

15 August 2017

Ting Ni

9

1 reference

15 August 2017

Yang Li

10

1 reference

15 August 2017

Han Yan

11

1 reference

15 August 2017

Jin-Pei Zhang

12

1 reference

15 August 2017

Chun Song

13

1 reference

15 August 2017

Li-Qing Chi

14

1 reference

15 August 2017

Han-Ming Wang

15

1 reference

15 August 2017

Jie Dong

16

1 reference

15 August 2017

Gu-Yan Zheng

17

1 reference

15 August 2017

Li Lin

18

1 reference

15 August 2017

Feng Qian

19

1 reference

15 August 2017

Yanwei Qi

20

1 reference

15 August 2017

Hongzhi Cao

22

1 reference

15 August 2017

Yinghao Wang

23

1 reference

15 August 2017

Lijuan Zhang

24

1 reference

15 August 2017

Zhaochun Li

25

1 reference

15 August 2017

Yufeng Zhou

26

1 reference

15 August 2017

Yan Wang

27

1 reference

15 August 2017

Jiehua Lu

28

1 reference

15 August 2017

Jianxin Li

29

1 reference

15 August 2017

Ming Qi

30

1 reference

15 August 2017

Kenneth C Land

33

1 reference

15 August 2017

Simon Gregory

34

1 reference

15 August 2017

Ze Yang

35

1 reference

15 August 2017

Wei Tao

37

1 reference

15 August 2017

Jian Wang

38

1 reference

15 August 2017

Jun Wang

39

1 reference

15 August 2017

Harold Bae

41

1 reference

15 August 2017

Lene Christiansen

43

1 reference

15 August 2017

Jun Gu

47

1 reference

15 August 2017

Huji Xu

54

1 reference

15 August 2017

Xiao-Li Tian

55

1 reference

15 August 2017

language of work or name

English

0 references

publication date

25 February 2016

1 reference

15 August 2017

1 reference

15 August 2017

6

1 reference

15 August 2017

21243

1 reference

Creative Commons Attribution 4.0 International

15 August 2017

start time

1 February 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity".

1 reference

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Proteasomes, Sir2, and Hxk2 form an interconnected aging network that impinges on the AMPK/Snf1-regulated transcriptional repressor Mig1.

30 September 2017

1 reference

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Calcium signaling, excitability, and synaptic plasticity defects in a mouse model of Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Alzheimer's disease genetics: from the bench to the clinic

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Extended maternal age at birth of last child and women's longevity in the Long Life Family Study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Dynamic regulation of genetic pathways and targets during aging in Caenorhabditis elegans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Towards Deeper Research and Better Policy for Healthy Aging --Using the Unique Data of Chinese Longitudinal Healthy Longevity Survey

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

STITCH 4: integration of protein-chemical interactions with user data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

The Genotype-Tissue Expression (GTEx) project

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

eXclusion: toward integrating the X chromosome in genome-wide association analyses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Health consequences of familial longevity influence among the Chinese elderly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Annotation of functional variation in personal genomes using RegulomeDB

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Analyzing age-specific genetic effects on human extreme age survival in cohort-based longitudinal studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Ten years of pathway analysis: current approaches and outstanding challenges

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genetic signatures of exceptional longevity in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

seeQTL: a searchable database for human eQTLs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

30 September 2017

Immunogenetics of ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Effects of FOXO genotypes on longevity: a biodemographic analysis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

METAL: fast and efficient meta-analysis of genomewide association scans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Common SNPs explain a large proportion of the heritability for human height

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Transcriptome genetics using second generation sequencing in a Caucasian population

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genomic dissection of population substructure of Han Chinese and its implication in association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

A genome-wide analysis of admixture in Uyghurs and a high-density admixture map for disease-gene discovery

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Exceptional longevity does not result in excessive levels of disability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Discerning the ancestry of European Americans in genetic association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

PLINK: a tool set for whole-genome association and population-based linkage analyses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

A new multipoint method for genome-wide association studies by imputation of genotypes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Reactome: a knowledgebase of biological pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

On estimating the relation between blood group and disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

30 September 2017

Estimating F-statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genomic control for association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Gene ontology: tool for the unification of biology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

KEGG: kyoto encyclopedia of genes and genomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Reduced apolipoprotein epsilon 4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Evolution. Getting to the root of aging.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Metformin slows down aging and extends life span of female SHR mice.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Genetic influence on human lifespan and longevity.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Age validation of Han Chinese centenarians.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

MAP kinase signalling cascade in Arabidopsis innate immunity.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4766491

Centenarians: the older you get, the healthier you have been

21 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP21243

Fructose and glucose differentially affect aging and carbonyl/oxidative stress parameters in Saccharomyces cerevisiae cells

21 January 2018

1 reference

12 December 2020

Paraoxonase 1 polymorphisms and survival

1 reference

12 December 2020

Association of late childbearing with healthy longevity among the oldest-old in China

1 reference

12 December 2020

The effect of age misreporting in China on the calculation of mortality rates at very high ages

1 reference

12 December 2020

The free-radical theory of ageing--older, wiser and still alive: modelling positional effects of the primary targets of ROS reveals new support

1 reference

12 December 2020

Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP21243

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

26912274

1 reference