(Q36620448)

English

Knockout of the c-Jun N-terminal Kinase 2 aggravates the development of mild chronic dextran sulfate sodium colitis independently of expression of intestinal cytokines TNFα, TGFB1, and IL-6.

scientific article published on 12 February 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Knockout of the c-Jun N-terminal Kinase 2 aggravates the development of mild chronic dextran sulfate sodium colitis independently of expression of intestinal cytokines TNFα, TGFB1, and IL-6. (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Sabine Kersting

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Kirstin Reinecke

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Christoph Hilgert

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Monika S Janot

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Elisabeth Haarmann

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Martin Albrecht

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Annette M Müller

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Thomas Herdegen

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ulrich Mittelkötter

9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Waldemar Uhl

10

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ansgar M Chromik

11

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

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publication date

12 February 2013

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Journal of Inflammation Research

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Europe PubMed Central

PMC publication ID

15 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

13-23

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

copyright license

Creative Commons Attribution-NonCommercial 3.0 Unported

1 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Distinct cytokine patterns identified from multiplex profiles of murine DSS and TNBS-induced colitis

1 reference

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30 September 2017

Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease

1 reference

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30 September 2017

Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

Targeting JNK for therapeutic benefit: from junk to gold?

1 reference

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30 September 2017

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

1 reference

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30 September 2017

Knockout mice: simple solutions to the problems of genetic background and flanking genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

c-Jun NH(2)-terminal kinase (JNK)1 and JNK2 signaling pathways have divergent roles in CD8(+) T cell-mediated antiviral immunity.

1 reference

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30 September 2017

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

1 reference

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30 September 2017

Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease

1 reference

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30 September 2017

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

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30 September 2017

Signaling by the JNK group of MAP kinases. c-jun N-terminal Kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

Signal transduction by MAP kinases in T lymphocytes

1 reference

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30 September 2017

Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

Mast cell tumor necrosis factor alpha production is regulated by MEK kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

Mitogen-activated protein kinase pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

The MAPK signaling cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

30 September 2017

A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

28 June 2018

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

28 June 2018

Reduced susceptibility of mice overexpressing transforming growth factor alpha to dextran sodium sulphate induced colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

28 June 2018

Clinicopathologic study of dextran sulfate sodium experimental murine colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

28 June 2018

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

28 June 2018

Oral administration of taurolidine ameliorates chronic DSS colitis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

Pro-inflammatory signaling by Jun-N-terminal kinase in inflammatory bowel disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

Genetic inhibition or activation of JNK1/2 protects the myocardium from ischemia-reperfusion-induced cell death in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

Therapeutic promise of JNK ATP-noncompetitive inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

Specific pathophysiological functions of JNK isoforms in the brain

1 reference

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20 September 2018

JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

c-Jun NH(2)-terminal kinase (JNK)1 and JNK2 have distinct roles in CD8(+) T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

1 reference

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20 September 2018

Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576002

20 September 2018

The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic deletion of JNK1 and JNK2 aggravates the DSS-induced colitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective T Cell Differentiation in the Absence of Jnk1

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/23426157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2147/JIR.S36415

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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