(Q36621655)

English

Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases. The Melanoma Cooperative Group.

scientific article published on December 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104570%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases. The Melanoma Cooperative Group (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104570%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Giuseppe Palmieri

1

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2 November 2019

Antonio Giuseppe Maria Cossu

2

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2 November 2019

4

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2 November 2019

8

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2 November 2019

Melanoma Cooperative Group

13

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Melanoma Cooperative Group

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2 November 2019

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M Strazzullo

5

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2 November 2019

A Lissia

6

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2 November 2019

M Colombino

7

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2 November 2019

C Floris

9

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2 November 2019

F Tanda

10

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2 November 2019

M Pirastu

11

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2 November 2019

G Castello

12

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2 November 2019

P A Ascierto

3

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2 November 2019

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1 December 2000

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2 November 2019

British Journal of Cancer

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104570%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

83

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2 November 2019

12

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2 November 2019

1707-1714

1 reference

Europe PubMed Central

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2 November 2019

Identification of a founder BRCA2 mutation in Sardinia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Germ-line deletion involving the INK4 locus in familial proneness to melanoma and nervous system tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Low frequency of p16/CDKN2A methylation in sporadic melanoma: comparative approaches for methylation analysis of primary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

The CDKN2A (p16) gene and human cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

CDKN2A (p16INK4A) somatic and germline mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Homozygous deletions within human chromosome band 9p21 in melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

30 September 2017

Prognostic significance of allelic losses in primary melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

28 June 2018

Molecular genetics of familial cutaneous melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

28 June 2018

Melanoma epidemiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

28 June 2018

Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

28 June 2018

Deletion mapping of chromosome region 9p21-p22 surrounding the CDKN2 locus in melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

28 June 2018

Microsatellite instability and loss of heterozygosity in melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

28 June 2018

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

27 July 2018

Two target regions of allelic loss on chromosome 9 in urinary-bladder cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

20 September 2018

High frequency of deletion on chromosome 9p21 may harbor several tumor-suppressor genes in human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

20 September 2018

Melanoma and other skin neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

20 September 2018

Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

20 September 2018

Methylation and p16: suppressing the suppressor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

20 September 2018

Polymerase Chain Reaction-Based Detection of Circulating Melanoma Cells as an Effective Marker of Tumor Progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

4 December 2018

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363459

4 December 2018

Detection of microsatellite alterations in the spectrum of melanocytic nevi in patients with or without individual or family history of melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of heterozygosity in sporadic primary cutaneous melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Affected members of melanoma‐prone families with linkage to 9p21 but lacking mutations in CDKN2A do not harbor mutations in the coding regions of either CDKN2B or p19ARF

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening of germline mutations in the CDKN2A and CDKN2B genes in Swedish families with hereditary cutaneous melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic alterations of p16INK4a and p53 genes in sporadic dysplastic nevus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homozygous deletion of the p16INK4a and the p15INK4b tumour suppressor genes in a subset of human sporadic cutaneous malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retention of the CDKN2A locus and low frequency of point mutations in primary and metastatic cutaneous malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microsatellite instability in malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of genetic profiles between primary melanomas and their metastases reveals genetic alterations and clonal evolution during progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p16INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of expression of the p16/cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel germline p16 mutation in familial malignant melanoma in southern Sweden

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infrequent Mutation of p16INK4 in Sporadic Melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of tumor cell evolution in a melanoma: evidence of mutational and selective pressure for loss of p16ink4 and for microsatellite instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104570

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1054/BJOC.2000.1513

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104570%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104570%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104570%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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