(Q36622088)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22569366%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster (English)

1 reference

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31 January 2020

0 references

2

1 reference

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31 January 2020

Achim Breiling

8

1 reference

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31 January 2020

7

Frank Lyko

1 reference

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31 January 2020

author name string

Michael T Bocker

1

1 reference

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31 January 2020

Günter Raddatz

3

1 reference

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31 January 2020

Tanja Musch

4

1 reference

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31 January 2020

Feng-Chun Yang

5

1 reference

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31 January 2020

Mingjiang Xu

6

1 reference

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31 January 2020

language of work or name

English

0 references

publication date

8 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22569366%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

published in

Nature Communications

1 reference

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31 January 2020

volume

3

1 reference

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31 January 2020

page(s)

818

1 reference

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https://scigraph.springernature.com/pub.10.1038/ncomms1826

31 January 2020

exact match

0 references

cites work

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Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

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30 September 2017

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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

30 September 2017

1 reference

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Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

30 September 2017

1 reference

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

30 September 2017

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Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

30 September 2017

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

30 September 2017

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Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

30 September 2017

1 reference

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TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

30 September 2017

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Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

30 September 2017

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Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

30 September 2017

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Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus

30 September 2017

1 reference

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TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

30 September 2017

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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

30 September 2017

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Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid

30 September 2017

1 reference

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Retinoids regulate stem cell differentiation

30 September 2017

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Active DNA demethylation: many roads lead to Rome.

30 September 2017

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The three-dimensional architecture of Hox cluster silencing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

30 September 2017

1 reference

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Aging and chronic sun exposure cause distinct epigenetic changes in human skin

30 September 2017

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Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors

30 September 2017

1 reference

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Dynamic changes in the human methylome during differentiation

30 September 2017

1 reference

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The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing

30 September 2017

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Human DNA methylomes at base resolution show widespread epigenomic differences

30 September 2017

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Acquired mutations in TET2 are common in myelodysplastic syndromes

30 September 2017

1 reference

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

30 September 2017

1 reference

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Retinoic acid synthesis and signaling during early organogenesis

30 September 2017

1 reference

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Genome-scale DNA methylation maps of pluripotent and differentiated cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Epigenetic regulation of Hox gene activation: the waltz of methyls

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Assessment of pluripotency and multilineage differentiation potential of NTERA-2 cells as a model for studying human embryonic stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Epigenetic inactivation of the HOXA gene cluster in breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Core transcriptional regulatory circuitry in human embryonic stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Organizing axes in time and space; 25 years of colinear tinkering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

From teratocarcinomas to embryonic stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Colinearity and functional hierarchy among genes of the homeotic complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

HOX gene activation by retinoic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Sequencing of natural strains of Arabidopsis thaliana with short reads

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576573

Retinoic acid and homeobox gene regulation.

28 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1826

Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1826

The dynamic architecture of Hox gene clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1826

Methylated DNA immunoprecipitation (MeDIP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1826

21 January 2018

Identifiers

DOI

10.1038/NCOMMS1826

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22569366%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22569366%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22569366%20AND%20SRC:MED&resulttype=core&format=json