(Q36623081)

15 August 2017

1 reference

title

Novel therapies for rheumatoid arthritis (English)

1 reference

15 August 2017

1 reference

1

Adriana H Tremoulet

1 reference

15 August 2017

Salvatore Albani

2

1 reference

PubMed ID

17040201

15 August 2017

language of work or name

English

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publication date

1 November 2006

1 reference

Expert Opinion on Investigational Drugs

15 August 2017

1 reference

15 August 2017

15

1 reference

15 August 2017

1427-1441

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15 August 2017

11

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Rheumatoid arthritis. Pathophysiology and implications for therapy

15 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

An assessment of the annual and long-term direct costs of rheumatoid arthritis: the impact of poor function and functional decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Cytokine pathways and joint inflammation in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

T-cell regulation in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

How important are T cells in chronic rheumatoid synovitis?: II. T cell-independent mechanisms from beginning to end.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Chemokines and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Pathogenesis of rheumatoid arthritis. Role of B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Pathogenesis of rheumatoid arthritis: the role of synoviocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Chemokines in rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Chemokines and chemokine receptors in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Inhibition of fractalkine ameliorates murine collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Chemokine receptor expression in rat adjuvant-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

RANTES and chemotactic activity in synovial fluids from patients with rheumatoid arthritis and osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Amelioration of rat adjuvant-induced arthritis by Met-RANTES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Negative association between the chemokine receptor CCR5-Delta32 polymorphism and rheumatoid arthritis: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

The human specific CCR1 antagonist CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Pro- and anti-inflammatory cytokines in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic synovial biopsies: comparison with synovial samples from patients with end stage, destructive rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Infections in patients with rheumatoid arthritis treated with biologic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Granulomatous infectious diseases associated with tumor necrosis factor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Inhibitors of TACE and Caspase-1 as anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Characterization of (2R, 3S)-2-([[4-(2-butynyloxy)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-alpha converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Safety of extended treatment with anakinra in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Cytokine traps: multi-component, high-affinity blockers of cytokine action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Human anti-human IL-18 antibody recognizing the IL-18-binding site 3 with IL-18 signaling blocking activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Signal transduction via CD44: role of plasma membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Evidence in support of a self-perpetuating HLA-DR-dependent delayed-type cell reaction in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Transfer of rheumatoid arthritis into severe combined immunodeficient mice. The pathogenetic implications of T cell populations oligoclonally expanding in the rheumatoid joints

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Targeting T cell costimulation in autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

CTLA-4 ligation blocks CD28-dependent T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: twelve-month results of a phase iib, double-blind, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Specific suppression of T helper alloreactivity by allo-MHC class I-restricted CD8+CD28- T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Cell-based immunotherapy with suppressor CD8+ T cells in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Induction of IL-10-producing CD4+CD25+ T cells in animal model of collagen-induced arthritis by oral administration of type II collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Immunopotentiating heat shock proteins: negotiators between innate danger and control of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

The T cells specific for the carboxyl-terminal determinants of self (rat) heat-shock protein 65 escape tolerance induction and are involved in regulation of autoimmune arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

T-cell reactivity to human HSP60 in oligo-articular juvenile chronic arthritis is associated with a favorable prognosis and the generation of regulatory cytokines in the inflamed joint

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Role of nuclear factor-kappaB in the immune system and bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Inhibition of the mitogen activated protein kinase, p38 alpha, prevents proinflammatory cytokine induction by human adherent mononuclear leukocytes in response to lipid loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Effects of RWJ 67657, a p38 mitogen activated protein kinase (MAPK) inhibitor, on the production of inflammatory mediators by rheumatoid synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Effects and mechanisms of FR167653, a dual inhibitor of interleukin-1 and tumor necrosis factor, on adjuvant arthritis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Osteoclasts are essential for TNF-alpha-mediated joint destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

The Inhibitory Co-Receptor, PECAM-1 Provides a Protective Effect in Suppression of Collagen-Induced Arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.11.1427

10.1517/13543784.15.11.1427

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17040201