(Q36625767)

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Zinc finger function of HIV-1 nucleocapsid protein is required for removal of 5'-terminal genomic RNA fragments: a paradigm for RNA removal reactions in HIV-1 reverse transcription.

scientific article published on 10 November 2012

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17 February 2020

Zinc finger function of HIV-1 nucleocapsid protein is required for removal of 5'-terminal genomic RNA fragments: a paradigm for RNA removal reactions in HIV-1 reverse transcription (English)

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17 February 2020

viral nucleocapsid

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Yasumasa Iwatani

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17 February 2020

Robert J Gorelick

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Robert J Gorelick

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17 February 2020

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Christopher B Hergott

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17 February 2020

Mithun Mitra

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17 February 2020

Jianhui Guo

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17 February 2020

Tiyun Wu

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17 February 2020

Jennifer T Miller

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17 February 2020

Judith G Levin

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17 February 2020

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10 November 2012

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17 February 2020

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17 February 2020

171

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17 February 2020

2

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17 February 2020

346-355

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17 February 2020

Identification of HIV-1 inhibitors targeting the nucleocapsid protein.

1 reference

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Characterization of the inhibition mechanism of HIV-1 nucleocapsid protein chaperone activities by methylated oligoribonucleotides.

1 reference

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30 September 2017

Flexible nature and specific functions of the HIV-1 nucleocapsid protein

1 reference

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30 September 2017

Identification of a methylated oligoribonucleotide as a potent inhibitor of HIV-1 reverse transcription complex.

1 reference

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30 September 2017

Requirements for efficient minus strand strong-stop DNA transfer in human immunodeficiency virus 1.

1 reference

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30 September 2017

Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Biophysical studies of the nucleic acid chaperone properties of the HIV-1 nucleocapsid protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Fundamental differences between the nucleic acid chaperone activities of HIV-1 nucleocapsid protein and Gag or Gag-derived proteins: biological implications

1 reference

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30 September 2017

Retroviral reverse transcriptases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Inhibition of HIV-1 replication by a bis-thiadiazolbenzene-1,2-diamine that chelates zinc ions from retroviral nucleocapsid zinc fingers

1 reference

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30 September 2017

Maturation of the HIV reverse transcription complex: putting the jigsaw together

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein

1 reference

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30 September 2017

Fidelity of plus-strand priming requires the nucleic acid chaperone activity of HIV-1 nucleocapsid protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition

1 reference

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30 September 2017

A new role for HIV nucleocapsid protein in modulating the specificity of plus strand priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Strand transfer events during HIV-1 reverse transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Nucleocapsid protein function in early infection processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Effects of nucleic acid local structure and magnesium ions on minus-strand transfer mediated by the nucleic acid chaperone activity of HIV-1 nucleocapsid protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Nucleic acid chaperone activity of HIV-1 nucleocapsid protein: critical role in reverse transcription and molecular mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

The chaperoning and assistance roles of the HIV-1 nucleocapsid protein in proviral DNA synthesis and maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Specific zinc-finger architecture required for HIV-1 nucleocapsid protein's nucleic acid chaperone function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Subtle alterations of the native zinc finger structures have dramatic effects on the nucleic acid chaperone activity of human immunodeficiency virus type 1 nucleocapsid protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

In vitro analysis of human immunodeficiency virus type 1 minus-strand strong-stop DNA synthesis and genomic RNA processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Zinc finger structures in the human immunodeficiency virus type 1 nucleocapsid protein facilitate efficient minus- and plus-strand transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Human immunodeficiency virus type 1 nucleocapsid protein can prevent self-priming of minus-strand strong stop DNA by promoting the annealing of short oligonucleotides to hairpin sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Sequences in the 5' and 3' R elements of human immunodeficiency virus type 1 critical for efficient reverse transcription

1 reference

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30 September 2017

Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: stimulation by the viral nucleocapsid protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Molecular requirements for human immunodeficiency virus type 1 plus-strand transfer: analysis in reconstituted and endogenous reverse transcription systems

1 reference

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30 September 2017

Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578084

30 September 2017

Human immunodeficiency virus type 1 nucleocapsid protein promotes efficient strand transfer and specific viral DNA synthesis by inhibiting TAR-dependent self-priming from minus-strand strong-stop DNA.

1 reference

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30 September 2017

Possible roles of HIV-1 nucleocapsid protein in the specificity of proviral DNA synthesis and in its variability

1 reference

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Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors

1 reference

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Utilization of nonhomologous minus-strand DNA transfer to generate recombinant retroviruses

1 reference

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Human immunodeficiency virus type 1 nucleocapsid protein reduces reverse transcriptase pausing at a secondary structure near the murine leukemia virus polypurine tract

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The two zinc fingers in the human immunodeficiency virus type 1 nucleocapsid protein are not functionally equivalent

1 reference

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DNA strand exchange and selective DNA annealing promoted by the human immunodeficiency virus type 1 nucleocapsid protein

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1 reference

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Premature strand transfer by the HIV-1 reverse transcriptase during strong-stop DNA synthesis

1 reference

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1 reference

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Evidence of interactions between the nucleocapsid protein NCp7 and the reverse transcriptase of HIV-1.

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Point mutations in conserved amino acid residues within the C-terminal domain of HIV-1 reverse transcriptase specifically repress RNase H function

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Substrate requirements for secondary cleavage by HIV-1 reverse transcriptase RNase H.

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Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesis

1 reference

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Steps of the acceptor invasion mechanism for HIV-1 minus strand strong stop transfer

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7 January 2021

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7 January 2021

A detailed model of reverse transcription and tests of crucial aspects

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.08.013

7 January 2021

Alteration of nucleic acid structure and stability modulates the efficiency of minus-strand transfer mediated by the HIV-1 nucleocapsid protein

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7 January 2021

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7 January 2021

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10.1016/J.VIRUSRES.2012.08.013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23149014%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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17 February 2020

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17 February 2020

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