(Q36625933)

15 August 2017

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title

Peptide-based inhibitors of amyloid assembly (English)

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15 August 2017

author name string

Kimberly L Sciarretta

series ordinal

1

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15 August 2017

David J Gordon

series ordinal

2

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15 August 2017

Stephen C Meredith

series ordinal

3

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15 August 2017

language of work or name

English

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publication date

1 January 2006

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15 August 2017

published in

Methods in Enzymology

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15 August 2017

volume

413

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15 August 2017

page(s)

273-312

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Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease

15 August 2017

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Synthetic preparation of N-methyl-alpha-amino acids

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Direct observation of Abeta amyloid fibril growth and inhibition

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7 January 2021

Immunization therapy for Alzheimer disease?

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7 January 2021

1H nuclear magnetic resonance determination of the membrane-bound conformation of senktide, a highly selective neurokinin B agonist

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Convenient synthesis of N-methylamino acids compatible with Fmoc solid-phase peptide synthesis

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7 January 2021

Inhibition of fibril formation and toxicity of a fragment of alpha-synuclein by an N-methylated peptide analogue

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7 January 2021

Affinity-Based Inhibition of β-Amyloid Toxicity†

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7 January 2021

Kinetic analysis of beta-amyloid fibril elongation

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7 January 2021

Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides

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7 January 2021

Stereoselective interactions of peptide inhibitors with the beta-amyloid peptide

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7 January 2021

Measurements of residual dipolar couplings in peptide inhibitors weakly aligned by transient binding to peptide amyloid fibrils

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7 January 2021

Cylindrical β-Sheet Peptide Assemblies

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7 January 2021

Inhibition of amyloid fiber assembly by both BiP and its target peptide

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7 January 2021

"One-pot" methylation of N-Nosyl-alpha-amino acid methyl esters with diazomethane and their coupling to prepare N-methyl dipeptides

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7 January 2021

A strategy for designing inhibitors of alpha-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders

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7 January 2021

Evidence for the bioactive conformation in a cyclic hexapeptide analogue of somatostatin containing a cis-peptide bond mimic

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7 January 2021

The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation

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7 January 2021

Modified-peptide inhibitors of amyloid beta-peptide polymerization

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7 January 2021

Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis

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7 January 2021

Beta-amyloid-derived pentapeptide RIIGLa inhibits Abeta(1-42) aggregation and toxicity

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7 January 2021

Immunotherapy for Alzheimer's disease

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7 January 2021

A strategy for designing inhibitors of beta-amyloid toxicity

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7 January 2021

Inhibition of amyloid fibril formation by peptide analogues modified with alpha-aminoisobutyric acid

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7 January 2021

Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.

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7 January 2021

Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Computed circular dichroism spectra for the evaluation of protein conformation

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Kinetic modeling and determination of reaction constants of Alzheimer's beta-amyloid fibril extension and dissociation using surface plasmon resonance.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Pentapeptide amides interfere with the aggregation of beta-amyloid peptide of Alzheimer's disease.

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7 January 2021

Origin of slow conformer conversion of triostin A and interaction ability with nucleic acid bases

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7 January 2021

Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides

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7 January 2021

A thyrotropin-releasing hormone analogue: pGlu-Phe-D-Pro-psi [CN4]-NMe at 293 and 107 K

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7 January 2021

Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Two-hybrid system as a model to study the interaction of beta-amyloid peptide monomers

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Polydepsipeptides. III. Theoretical conformational analysis of randomly coiling and ordered depsipeptide chains.

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7 January 2021

Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation

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7 January 2021

Structural characteristics of alpha-helical peptide molecules containing Aib residues

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7 January 2021

Sequence-specific polypeptoids: a diverse family of heteropolymers with stable secondary structure

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7 January 2021

On the nucleation of amyloid beta-protein monomer folding

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7 January 2021

1H NMR of A beta amyloid peptide congeners in water solution. Conformational changes correlate with plaque competence

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7 January 2021

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

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7 January 2021

Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF.

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7 January 2021

Probing intermolecular main chain hydrogen bonding in serine proteinase-protein inhibitor complexes: chemical synthesis of backbone-engineered turkey ovomucoid third domain

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7 January 2021

Simulation study of the structure and dynamics of the Alzheimer's amyloid peptide congener in solution

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7 January 2021

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

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7 January 2021

Effects of sequential proline substitutions on amyloid formation by human amylin20-29.

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7 January 2021

The peptide KLVFF-K(6) promotes beta-amyloid(1-40) protofibril growth by association but does not alter protofibril effects on cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT).

1 reference

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7 January 2021

Analysis of fibril elongation using surface plasmon resonance biosensors

1 reference

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7 January 2021

Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening

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7 January 2021

Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

N-methylleucine gramicidin-S and (di-N-methylleucine) gramicidin-S conformations withcisL-Orn-L-N-MeLeu peptide bonds

1 reference

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7 January 2021

Conformational analysis of mu-selective [D-Ala2,MePhe4]enkephalins

1 reference

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7 January 2021

Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions

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7 January 2021

Neutrophil activation by monomeric interleukin-8.

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7 January 2021

Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides

1 reference

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7 January 2021

Prevention of Alzheimer's disease-associated Abeta aggregation by rationally designed nonpeptidic beta-sheet ligands

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7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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7 January 2021

Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid

1 reference

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7 January 2021

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy

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7 January 2021

Arrest of beta-amyloid fibril formation by a pentapeptide ligand

1 reference

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7 January 2021

Controlling amyloid beta-peptide fibril formation with protease-stable ligands

1 reference

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7 January 2021

Stability of cis and trans amide bond conformations in polypeptides

1 reference

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7 January 2021

N-methyl peptides. III. Solution conformational study and crystal structure of N-pivaloyl-L-prolyl-N-methyl-N'-isopropyl-L-alaninamide

1 reference

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7 January 2021

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

1 reference

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7 January 2021

Facile synthesis of highly functionalized N-methyl amino acid esters without side-chain protection

1 reference

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7 January 2021

Mapping abeta amyloid fibril secondary structure using scanning proline mutagenesis

1 reference

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7 January 2021

Prolines and amyloidogenicity in fragments of the Alzheimer's peptide beta/A4

1 reference

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7 January 2021

Structural and Spectroscopic Studies of Peptoid Oligomers with α-Chiral Aliphatic Side Chains

1 reference

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7 January 2021

Inhibition of peptide amyloid formation by cationic peptides with homologous sequences

1 reference

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7 January 2021

Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Methodological and chemical factors affecting amyloid beta peptide amyloidogenicity.

1 reference

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7 January 2021

The Alzheimer's peptide a beta adopts a collapsed coil structure in water

1 reference

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7 January 2021

How small peptides block and reverse serpin polymerisation.

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7 January 2021

The nucleation of monomeric parallel beta-sheet-like structures and their self-assembly in aqueous solution

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7 January 2021

Inhibition of beta-amyloid toxicity by short peptides containing N-methyl amino acids.

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7 January 2021

Inhibition of toxicity and protofibril formation in the amyloid-beta peptide beta(25-35) using N-methylated derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Disruption of the beta-sheet structure of a protected pentapeptide, related to the beta-amyloid sequence 17-21, induced by a single, helicogenic C(alpha)-tetrasubstituted alpha-amino acid

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Mechanistic studies of the process of amyloid fibrils formation by the use of peptide fragments and analogues: implications for the design of fibrillization inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Conformational and spectral analysis of the polypeptide antibiotic N-methylleucine gramicidin S dihydrochloride by nuclear magnetic resonance

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Controlling polymerization of beta-amyloid and prion-derived peptides with synthetic small molecule ligands.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Design strategies for anti-amyloid agents.

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7 January 2021

Growth of beta-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Thermodynamics of A beta(1-40) amyloid fibril elongation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

Amyloid fibril formation by A beta 16-22, a seven-residue fragment of the Alzheimer's beta-amyloid peptide, and structural characterization by solid state NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2913015-3

7 January 2021

10.1016/S0076-6879(06)13015-3

Identifiers

DOI

1 reference

15 August 2017

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