(Q36631660)

15 August 2017

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title

Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy (English)

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15 August 2017

4

Eva L Feldman

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15 August 2017

Gina M Leinninger

1

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15 August 2017

James L Edwards

series ordinal

2

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15 August 2017

Matthew J Lipshaw

series ordinal

3

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15 August 2017

publication date

1 November 2006

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15 August 2017

number of pages

9

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Nature Clinical Practice Neurology

inferred from page(s)

published in

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15 August 2017

volume

2

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15 August 2017

issue

11

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15 August 2017

page(s)

620-628

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Molecular understanding of hyperglycemia's adverse effects for diabetic complications

15 August 2017

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Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance

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Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction

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Does diabetes target ganglion neurones? Progressive sensory neurone involvement in long-term experimental diabetes

21 January 2018

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Apoptosis in the developing visual system

21 January 2018

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Bcl-2 family gene products in cerebral ischemia and traumatic brain injury

21 January 2018

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Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL.

21 January 2018

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

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Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

21 January 2018

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Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

21 January 2018

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

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Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells.

21 January 2018

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Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage

21 January 2018

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Mitochondrial morphology is dynamic and varied

21 January 2018

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Dynamics of mitochondrial morphology in healthy cells and during apoptosis

21 January 2018

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Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

21 January 2018

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Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

21 January 2018

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Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The continuing epidemics of obesity and diabetes in the United States

21 January 2018

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7 January 2021

Short-term hyperglycemia produces oxidative damage and apoptosis in neurons

1 reference

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7 January 2021

Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons.

1 reference

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7 January 2021

Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1

1 reference

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7 January 2021

Identifiers

DOI

10.1038/NCPNEURO0320

1 reference

Dimensions Publication ID

15 August 2017

1006792979

0 references

1 reference