(Q36640026)

15 August 2017

The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment (English)

1 reference

15 August 2017

Charlotte Rolny

1

0 references

Massimiliano Mazzone

Massimiliano Mazzone

4

0 references

Luca Tamagnone

Luca Tamagnone

10

0 references

Paolo M. Comoglio

Paolo M Comoglio

9

0 references

Peter Carmeliet

8

Peter Carmeliet

1 reference

15 August 2017

Lorena Capparuccia

2

1 reference

15 August 2017

Andrea Casazza

3

1 reference

15 August 2017

Antonella Vallario

5

1 reference

15 August 2017

Alessandro Cignetti

6

1 reference

15 August 2017

Enzo Medico

7

1 reference

15 August 2017

language of work or name

English

0 references

publication date

5 May 2008

1 reference

Journal of Experimental Medicine

15 August 2017

1 reference

15 August 2017

205

1 reference

15 August 2017

1155-1171

1 reference

15 August 2017

5

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2373847/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding

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Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells.

30 September 2017

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Tumor promotion by tumor-associated macrophages

30 September 2017

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30 September 2017

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Semaphorin signaling in vascular and tumor biology

21 January 2018

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Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

30 September 2017

1 reference

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Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest

30 September 2017

1 reference

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A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells

30 September 2017

1 reference

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MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research

30 September 2017

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STAT1 acts as a tumor promoter for leukemia development

30 September 2017

1 reference

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

30 September 2017

1 reference

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The neuropilins and their role in tumorigenesis and tumor progression

30 September 2017

1 reference

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Semaphorins command cells to move

30 September 2017

1 reference

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Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

30 September 2017

1 reference

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Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells.

30 September 2017

1 reference

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Proteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasis

30 September 2017

1 reference

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The CXCR1 tail mediates beta1 integrin-dependent cell migration via MAP kinase signaling

30 September 2017

1 reference

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Macrophage receptors and immune recognition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

The role of interleukin-8 in cancer cells and microenvironment interaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Targeting the tumor and its microenvironment by a dual-function decoy Met receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Stress-activated protein kinases-tumor suppressors or tumor initiators?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

To move or not to move? Semaphorin signalling in cell migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Multiple control of interleukin-8 gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Combined administration of antibodies to human interleukin 8 and epidermal growth factor receptor results in increased antimetastatic effects on human breast carcinoma xenografts.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

HIV-based vectors. Preparation and use.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Robust and efficient regulation of transgene expression in vivo by improved tetracycline-dependent lentiviral vectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Gene expression profiling predicts clinical outcome of breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Interleukin-8 and human cancer biology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Interleukin-8: an expanding universe beyond neutrophil chemotaxis and activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Neuropilin is a semaphorin III receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

Semaphorin-3F is an inhibitor of tumor angiogenesis.

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Dual functional activity of semaphorin 3B is required for positioning the anterior commissure

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Novel genes associated with malignant melanoma but not benign melanocytic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Interleukin 8 in human hepatocellular carcinoma correlates with cancer cell invasion of vessels but not with tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Interleukin-8 differentially regulates migration of tumor-associated and normal human brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Expression of CXCR1 and CXCR2 receptors in malignant melanoma with different metastatic potential and their role in interleukin-8 (CXCL-8)-mediated modulation of metastatic phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Pericytes limit tumor cell metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

The characterization of chemokine production and chemokine receptor expression reveals possible functional cross-talks in AML blasts with monocytic differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373847

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

20 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20072509

Interleukin‐8 secreted by endothelial cells induces Chemotaxis of melanoma cells through the chemokine receptor CXCR1

21 January 2018

1 reference

12 December 2020

Mucosal IL-8 and TGF-beta recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells

1 reference

12 December 2020

Upregulation of interleukin-8 and polarized epithelial expression of interleukin-8 receptor A in ovarian carcinomas

1 reference

12 December 2020

HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells

1 reference

12 December 2020

Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20072509

1 reference

15 August 2017

1 reference

15 August 2017

1 reference