(Q36642766)

English

Unique neuronal functions of cathepsin L and cathepsin B in secretory vesicles: biosynthesis of peptides in neurotransmission and neurodegenerative disease

scientific article published on October 2006

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scholarly article

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Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

Unique neuronal functions of cathepsin L and cathepsin B in secretory vesicles: biosynthesis of peptides in neurotransmission and neurodegenerative disease (English)

1 reference

Europe PubMed Central

15 August 2017

neurodegeneration

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based on heuristic

inferred from title

author name string

Vivian Y H Hook

1

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Europe PubMed Central

15 August 2017

publication date

1 October 2006

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Europe PubMed Central

15 August 2017

Biological Chemistry

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Europe PubMed Central

15 August 2017

387

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Europe PubMed Central

15 August 2017

10-11

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Europe PubMed Central

15 August 2017

1429-1439

1 reference

Europe PubMed Central

15 August 2017

Neuropeptides and obesity

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Defective prodynorphin processing in mice lacking prohormone convertase PC2.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Endogenous opiates and behavior: 2004.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Genetic inactivation of prohormone convertase (PC1) causes a reduction in cholecystokinin (CCK) levels in the hippocampus, amygdala, pons and medulla in mouse brain that correlates with the degree of colocalization of PC1 and CCK mRNA in these struc

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Role of pituitary POMC-peptides and insulin-like growth factor II in the developmental biology of the adrenal gland

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Cholinergic agonists stimulate secretion of soluble full-length amyloid precursor protein in neuroendocrine cells

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Isolation and sequence analysis of cDNA for rat carboxypeptidase E [EC 3.4.17.10], a neuropeptide processing enzyme

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Serpin structure, mechanism, and function

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Carboxypeptidase B-like converting enzyme activity in secretory granules of rat pituitary

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Cysteine proteases are the major β‐secretase in the regulated secretory pathway that provides most of the β‐amyloid in Alzheimer's disease: Role of BACE 1 in the constitutive secretory pathway

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Immunochemical characterization of carboxypeptidase B-like peptide-hormone-processing enzyme

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Molecular cloning of endopin 1, a novel serpin localized to neurosecretory vesicles of chromaffin cells. Inhibition of basic residue-cleaving proteases by endopin 1.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Demonstration of GTG as an alternative initiation codon for the serpin endopin 2B-2.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Processing and activation of lysosomal proteinases

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Hypothalamic-pituitary-adrenocortical axis regulation

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Opioids and pain

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Identity and function of γ‐secretase

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Serpinopathies and the conformational dementias

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Obliteration of alpha-melanocyte-stimulating hormone derived from POMC in pituitary and brains of PC2-deficient mice

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The Therapeutic Potential of Neuropeptide Y : Analgesic, Anxiolytic and Antihypertensive

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Neuropeptide processing profile in mice lacking prohormone convertase-1.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

"Prohormone thiol protease" (PTP) processing of recombinant proenkephalin

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Galanin and spatial learning in the rat. Evidence for a differential role for galanin in subregions of the hippocampal formation.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Alzheimer's disease: perspectives for the new millennium

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The proprotein convertases

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Lysosomal cysteine proteases: more than scavengers

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The role of neuropeptide Y in cardiovascular regulation

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

The role of NPY in metabolic homeostasis: implications for obesity therapy

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Distinct presenilin‐dependent and presenilin‐independent γ‐secretases are responsible for total cellular Aβ production

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Evidence for the proenkephalin processing enzyme prohormone thiol protease (PTP) as a multicatalytic cysteine protease complex: activation by glutathione localized to secretory vesicles

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Proteolytic processing in the secretory pathway

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.179

21 January 2018

Identifiers

10.1515/BC.2006.179

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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