(Q36644877)

English

Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy

scientific article published on 28 December 2015

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy (English)

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Europe PubMed Central

PMC publication ID

15 August 2017

anti-retroviral agent

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Simian immunodeficiency virus

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1 reference

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object named as

Jeremy Smedley

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19

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Brandon F Keele

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Claire Deleage

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15 August 2017

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Jeffrey D Lifson

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15 August 2017

Gregory Q Del Prete

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Gregory Q Del Prete

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15 August 2017

Charles M Trubey

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Charles M Trubey

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15 August 2017

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Kelli Oswald

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Jacob D Estes

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15 August 2017

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Michael Piatak

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Abigail Lara

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Rebecca Shoemaker

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Rhonda Macallister

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Vicky Coalter

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Adam Wiles

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Rodney Wiles

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Yuan Li

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Randy Fast

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Rebecca Kiser

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Bing Lu

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Jim Zheng

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W Gregory Alvord

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Joseph Hesselgesser

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Romas Geleziunas

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15 August 2017

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publication date

28 December 2015

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15 August 2017

Antimicrobial Agents and Chemotherapy

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15 August 2017

60

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15 August 2017

3

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15 August 2017

1560-1572

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15 August 2017

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776002

30 September 2017

Short Communication: Comparative Evaluation of Coformulated Injectable Combination Antiretroviral Therapy Regimens in Simian Immunodeficiency Virus-Infected Rhesus Macaques

1 reference

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30 September 2017

Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.

1 reference

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30 September 2017

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

1 reference

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30 September 2017

Impact of antiretroviral therapy (ART) timing on chronic immune activation/inflammation and end-organ damage

1 reference

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30 September 2017

Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy

1 reference

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30 September 2017

Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques

1 reference

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30 September 2017

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

1 reference

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30 September 2017

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

1 reference

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30 September 2017

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

1 reference

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30 September 2017

HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat

1 reference

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30 September 2017

Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size

1 reference

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30 September 2017

HIV-1 eradication strategies: design and assessment

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30 September 2017

Considerations in the development of nonhuman primate models of combination antiretroviral therapy for studies of AIDS virus suppression, residual virus, and curative strategies

1 reference

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30 September 2017

Lost in transcription: molecular mechanisms that control HIV latency

1 reference

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30 September 2017

Antiretroviral therapy initiated during acute HIV infection fails to prevent persistent T-cell activation

1 reference

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30 September 2017

Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection

1 reference

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30 September 2017

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

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30 September 2017

HIV and inflammation: mechanisms and consequences

1 reference

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30 September 2017

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

1 reference

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30 September 2017

Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques

1 reference

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30 September 2017

Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells

1 reference

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30 September 2017

Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication

1 reference

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Financing equitable access to antiretroviral treatment in South Africa

1 reference

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30 September 2017

Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection

1 reference

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30 September 2017

Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction

1 reference

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30 September 2017

Combinatorial latency reactivation for HIV-1 subtypes and variants

1 reference

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Racial and sex disparities in life expectancy losses among HIV-infected persons in the united states: impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy.

1 reference

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30 September 2017

Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

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Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

1 reference

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A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression

1 reference

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The challenge of finding a cure for HIV infection

1 reference

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30 September 2017

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

1 reference

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Population pharmacokinetics of romidepsin in patients with cutaneous T-cell lymphoma and relapsed peripheral T-cell lymphoma

1 reference

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30 September 2017

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

1 reference

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Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies

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Changes in the risk of death after HIV seroconversion compared with mortality in the general population

1 reference

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Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects.

1 reference

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30 September 2017

Chromatin-associated regulation of HIV-1 transcription: implications for the development of therapeutic strategies

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Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression

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T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy

1 reference

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1 reference

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30 September 2017

HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression

1 reference

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30 September 2017

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1 reference

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Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

1 reference

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1 reference

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1 reference

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1 reference

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28 June 2018

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1 reference

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1 reference

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1 reference

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1 reference

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20 September 2018

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1 reference

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4 December 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study to determine the effects of food and multiple dosing on the pharmacokinetics of vorinostat given orally to patients with advanced cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26711758

12 December 2020

based on heuristic

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Identifiers

10.1128/AAC.02625-15

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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