(Q36649681)

15 August 2017

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title

Gene therapy targeting to tumor endothelium (English)

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15 August 2017

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M Bazan-Peregrino

1

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15 August 2017

L W Seymour

series ordinal

2

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15 August 2017

A L Harris

series ordinal

3

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15 August 2017

10 November 2006

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15 August 2017

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15 August 2017

14

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15 August 2017

117-127

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15 August 2017

2

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https://scigraph.springernature.com/pub.10.1038/sj.cgt.7701001

15 August 2017

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cites work

Angiogenesis in cancer and other diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Angiogenesis: update 2005.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Novel angiogenic signaling pathways and vascular targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Intussusceptive angiogenesis: its emergence, its characteristics, and its significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Origins of circulating endothelial cells and endothelial outgrowth from blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

CD133 positive endothelial progenitor cells contribute to the tumour vasculature in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

The role of adrenomedullin in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Vascular zip codes in angiogenesis and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Selective targeted delivery of TNFalpha to tumor blood vessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Signaling of the tissue factor coagulation pathway in angiogenesis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

The urokinase plasminogen activator system: role in malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Fibrinogen and fibrin structure and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Endogenous angiogenesis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Vascular targeting agents as cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Adenovirus type 5 interactions with human blood cells may compromise systemic delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Ablating CAR and integrin binding in adenovirus vectors reduces nontarget organ transduction and permits sustained bloodstream persistence following intraperitoneal administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

In vivo hepatic adenoviral gene delivery occurs independently of the coxsackievirus-adenovirus receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

The alphavbeta5 integrin of hematopoietic and nonhematopoietic cells is a transduction receptor of RGD-4C fiber-modified adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Targeting of high-capacity adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Dressing up adenoviruses to modify their tropism.. Interview by Florence Paillard

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Enhanced gene transfer activity of peptide-targeted gene-delivery vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Tumor regression by targeted gene delivery to the neovasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

A novel strategy to modify adenovirus tropism and enhance transgene delivery to activated vascular endothelial cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

CD46 is a cellular receptor for group B adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Improved adenovirus vectors for infection of cardiovascular tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Development and assessment of human adenovirus type 11 as a gene transfer vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Surface-engineering of lentiviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Development of lentiviral vectors for antiangiogenic gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Retroviral hybrid LTR vector strategy: functional analysis of LTR elements and generation of endothelial cell specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Expression of thymidine kinase driven by an endothelial-specific promoter inhibits tumor growth of Lewis lung carcinoma cells in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Hypoxia-mediated tumour targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Kinase domain insert containing receptor promotor controlled suicide gene system kills human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Use of von Willebrand factor promoter to transduce suicidal gene to human endothelial cells, HUVEC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Hypoxia-inducible regulation of a prodrug-activating enzyme for tumor-specific gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Transcription-controlled gene therapy against tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Endothelial cell-specific expression of tumor necrosis factor-alpha from the KDR or E-selectin promoters following retroviral delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Antiangiogenic gene therapy: disruption of neovascular networks mediated by inducible caspase-9 delivered with a transcriptionally targeted adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Herpes simplex virus amplicon delivery of a hypoxia-inducible angiogenic inhibitor blocks capillary formation in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Transcriptional targeting of conditionally replicating adenovirus to dividing endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

A novel hypoxia-inducible factor (HIF) activated oncolytic adenovirus for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Dual targeting of gene delivery by genetic modification of adenovirus serotype 5 fibers and cell-selective transcriptional control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Inhibition of orthotopic human bladder tumor growth by lentiviral gene transfer of endostatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Therapeutic effects of viral vector-mediated antiangiogenic gene transfer in malignant ascites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Adenovirus-mediated gene therapy with an antiangiogenic fragment of thrombospondin-1 inhibits human leukemia xenograft growth in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Systemic gene therapy with anti-angiogenic factors inhibits spontaneous breast tumor growth and metastasis in MMTVneu transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

The application of an anti-angiogenic gene (thrombospondin-1) in the treatment of human prostate cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Fibulins 3 and 5 antagonize tumor angiogenesis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Vascular endothelial growth inhibitor (VEGI), an endogenous negative regulator of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

PEX-producing human neural stem cells inhibit tumor growth in a mouse glioma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Genes expressed in human tumor endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Angiogenesis in life, disease and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Contribution of bone marrow–derived endothelial cells to human tumor vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Modification of an adenoviral vector with biologically selected peptides: a novel strategy for gene delivery to cells of choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

Targeting diphtheria toxin A-chain transcription to activated endothelial cells using an E-selectin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

inferred from DOI database lookup

7 January 2021

based on heuristic

A Hybrid Vector for Ligand-Directed Tumor Targeting and Molecular Imaging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7701001

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CGT.7701001

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference