(Q44306369)

English

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

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scholarly article

1 reference

Europe PubMed Central

1 December 2017

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors (English)

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Europe PubMed Central

1 December 2017

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inferred from title

Nico van Rooijen

5

object named as

Nico van Rooijen

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Europe PubMed Central

1 December 2017

author name string

Gudrun Schiedner

1

1 reference

Europe PubMed Central

1 December 2017

Sabine Hertel

2

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Europe PubMed Central

1 December 2017

Marion Johnston

3

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Europe PubMed Central

1 December 2017

Volker Dries

4

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Europe PubMed Central

1 December 2017

Stefan Kochanek

6

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Europe PubMed Central

1 December 2017

publication date

1 January 2003

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Europe PubMed Central

1 December 2017

Molecular Therapy

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Europe PubMed Central

1 December 2017

7

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Europe PubMed Central

1 December 2017

1

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Europe PubMed Central

1 December 2017

35-43

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Europe PubMed Central

1 December 2017

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis

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Inhibition of tumor necrosis factor alpha decreases inflammation and prolongs adenovirus gene expression in lung and liver

1 reference

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7 January 2021

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Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

1 reference

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7 January 2021

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A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency

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Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

1 reference

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Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

1 reference

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7 January 2021

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Successful expression of human factor IX following repeat administration of adenoviral vector in mice.

1 reference

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Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors

1 reference

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Gene therapy for hemophilia B: host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression

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Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung.

1 reference

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Transient immunosuppression with FK506 permits long-term expression of therapeutic genes introduced into the liver using recombinant adenoviruses in the rat.

1 reference

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7 January 2021

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Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactions

1 reference

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7 January 2021

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Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

1 reference

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Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration

1 reference

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High-capacity adenoviral vectors for gene transfer and somatic gene therapy

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An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene

1 reference

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High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

1 reference

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7 January 2021

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Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

1 reference

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7 January 2021

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Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector

1 reference

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7 January 2021

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Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

1 reference

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7 January 2021

based on heuristic

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Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2802%2900017-5

7 January 2021

based on heuristic

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Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2802%2900017-5

7 January 2021

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Blood clearance rates of adenovirus type 5 in mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

1 reference

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7 January 2021

based on heuristic

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Macrophage depletion increases the safety, efficacy and persistence of adenovirus-mediated gene transfer in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2802%2900017-5

7 January 2021

based on heuristic

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Effects of macrophage depletion and anti-CD40 ligand on transgene expression and redosing with recombinant adenovirus

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2802%2900017-5

7 January 2021

based on heuristic

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An immunomodulatory procedure that stabilizes transgene expression and permits readministration of E1-deleted adenovirus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2802%2900017-5

7 January 2021

based on heuristic

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Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Elimination, blocking, and activation of macrophages: three of a kind?

1 reference

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7 January 2021

based on heuristic

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Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2802%2900017-5

7 January 2021

based on heuristic

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Variables affecting in vivo performance of high-capacity adenovirus vectors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal

1 reference

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A DNA-based method to assay total and infectious particle contents and helper virus contamination in high-capacity adenoviral vector preparations

1 reference

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7 January 2021

based on heuristic

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Adenovirus-mediated gene transfer into human hepatocytes: analysis of the biochemical functionality of transduced cells.

1 reference

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Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors

1 reference

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7 January 2021

based on heuristic

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RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

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based on heuristic

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Liver Sinusoidal Endothelial Cells Are Not Permissive for Adenovirus Type 5

1 reference

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Efficient adenovirus-mediated gene transfer into human blood monocyte-derived macrophages

1 reference

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Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract

1 reference

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Identifiers

10.1016/S1525-0016(02)00017-5

1 reference

Europe PubMed Central

1 December 2017

1 reference

Europe PubMed Central

1 December 2017

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