(Q36654098)

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Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV

scientific article published on 20 December 2012

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21 February 2020

Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV (English)

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21 February 2020

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21 February 2020

Ronald G Collman

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21 February 2020

Frederic D. Bushman

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21 February 2020

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Carl H June

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21 February 2020

Bruce L. Levine

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Bruce L Levine

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21 February 2020

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David Stein

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21 February 2020

Gwendolyn Binder-Scholl

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21 February 2020

Rithun Mukherjee

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21 February 2020

Troy Brady

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21 February 2020

Tessio Rebello

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21 February 2020

Laurent Humeau

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21 February 2020

Michael Kalos

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21 February 2020

Emmanouil Papasavvas

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21 February 2020

Luis J Montaner

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21 February 2020

Daniel Schullery

11

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21 February 2020

Farida Shaheen

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21 February 2020

Andrea L Brennan

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21 February 2020

Zhaohui Zheng

14

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21 February 2020

Julio Cotte

15

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21 February 2020

Vladimir Slepushkin

16

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21 February 2020

Elizabeth Veloso

17

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21 February 2020

Adonna Mackley

18

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21 February 2020

Wei-Ting Hwang

19

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21 February 2020

Faten Aberra

20

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21 February 2020

Jenny Zhan

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21 February 2020

Jean Boyer

22

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21 February 2020

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20 December 2012

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21 February 2020

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10

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21 February 2020

121

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21 February 2020

9

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21 February 2020

1524-1533

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21 February 2020

Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587318

30 September 2017

Secreted antiviral entry inhibitory (SAVE) peptides for gene therapy of HIV infection

1 reference

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30 September 2017

Survival of the fittest: positive selection of CD4+ T cells expressing a membrane-bound fusion inhibitor following HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587318

30 September 2017

HIV sequence variation associated with env antisense adoptive T-cell therapy in the hNSG mouse model

1 reference

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30 September 2017

Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy.

1 reference

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The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

1 reference

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30 September 2017

Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587318

30 September 2017

T cell receptor contact to restricting MHC molecules is a prerequisite for peripheral interclonal T cell competition

1 reference

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30 September 2017

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

1 reference

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30 September 2017

Genetic therapies against HIV.

1 reference

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30 September 2017

Gene transfer in humans using a conditionally replicating lentiviral vector

1 reference

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30 September 2017

Impact of gene-modified T cells on HIV infection dynamics

1 reference

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1 reference

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30 September 2017

Randomized, controlled trial of therapy interruption in chronic HIV-1 infection

1 reference

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30 September 2017

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

1 reference

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30 September 2017

Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance

1 reference

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30 September 2017

Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection

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30 September 2017

Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery

1 reference

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30 September 2017

A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread

1 reference

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30 September 2017

Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587318

28 June 2018

Virological failure and adherence to antiretroviral therapy in HIV-infected patients

1 reference

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28 June 2018

The role of TCR specificity and clonal competition during reconstruction of the peripheral T cell pool.

1 reference

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20 September 2018

Resistance of mature T cells to oncogene transformation

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20 September 2018

A Pilot Study Evaluating Time to CD4 T-cell Count <350 cells/mm3 After Treatment Interruption Following Antiretroviral Therapy ± Interleukin 2: Results of ACTG A5102

1 reference

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20 September 2018

Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol.

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20 September 2018

Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load

1 reference

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20 September 2018

Optimization of methods to assess human mucosal T-cell responses to HIV infection.

1 reference

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20 September 2018

Mixed Models for Assessing Correlation in the Presence of Replication

1 reference

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20 September 2018

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A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy

1 reference

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20 September 2018

Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement

1 reference

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20 September 2018

Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.

1 reference

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1 reference

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Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection

1 reference

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20 September 2018

Peaceful coexistence or clonal dominance?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23264589

12 December 2020

based on heuristic

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Estimating the benefit of an HIV-1 vaccine that reduces viral load set point

1 reference

https://pubmed.ncbi.nlm.nih.gov/23264589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that intermittent structured treatment interruption, but not immunization with ALVAC-HIV vCP1452, promotes host control of HIV replication: the results of AIDS Clinical Trials Group 5068

1 reference

https://pubmed.ncbi.nlm.nih.gov/23264589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23264589

12 December 2020

based on heuristic

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Identifiers

10.1182/BLOOD-2012-07-447250

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21 February 2020

1 reference

Europe PubMed Central

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21 February 2020

1 reference

Europe PubMed Central

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21 February 2020

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