(Q36655904)

15 August 2017

Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma (English)

1 reference

15 August 2017

0 references

22

Martin Hasselblatt

0 references

Lars Riedemann

Lars Riedemann

5

0 references

John D Martin

John D Martin

9

0 references

Euiheon Chung

Euiheon Chung

16

0 references

Yuhui Huang

Yuhui Huang

8

0 references

Thomas Schmidt

Thomas Schmidt

12

0 references

Matija Snuderl

Matija Snuderl

1

0 references

Peter Carmeliet

30

Peter Carmeliet

1 reference

15 August 2017

31

Rakesh K Jain

1 reference

15 August 2017

25

Napoleone Ferrara

1 reference

15 August 2017

28

Dai Fukumura

1 reference

15 August 2017

Nathaniel D Kirkpatrick

3

Nathaniel D Kirkpatrick

1 reference

15 August 2017

13

Christian T Farrar

1 reference

15 August 2017

14

Benjamin J Vakoc

1 reference

15 August 2017

Ana Batista

2

1 reference

15 August 2017

Carmen Ruiz de Almodovar

4

1 reference

15 August 2017

Elisa C Walsh

6

1 reference

15 August 2017

Rachel Anolik

7

1 reference

15 August 2017

Walid Kamoun

10

1 reference

15 August 2017

Ellen Knevels

11

1 reference

15 August 2017

Nishant Mohan

15

1 reference

15 August 2017

Sylvie Roberge

17

1 reference

15 August 2017

Teresa Peterson

18

1 reference

15 August 2017

Carlos Bais

19

1 reference

15 August 2017

Boryana H Zhelyazkova

20

1 reference

15 August 2017

Stephen Yip

21

1 reference

15 August 2017

Claudia Rossig

23

1 reference

15 August 2017

Elisabeth Niemeyer

24

1 reference

15 August 2017

Michael Klagsbrun

26

1 reference

15 August 2017

Dan G Duda

27

1 reference

15 August 2017

Lei Xu

29

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 February 2013

1 reference

15 August 2017

1 reference

15 August 2017

152

1 reference

15 August 2017

5

1 reference

15 August 2017

1065-1076

1 reference

Medulloblastomics: the end of the beginning

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

PlGF: a multitasking cytokine with disease-restricted activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Inhibition of placenta growth factor with TB-403: a novel antiangiogenic cancer therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Molecular subgroups of medulloblastoma: the current consensus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Hedgehog fights back: mechanisms of acquired resistance against Smoothened antagonists

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Normalization of the vasculature for treatment of cancer and other diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Molecular mechanisms and clinical applications of angiogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Tumor microvasculature and microenvironment: novel insights through intravital imaging in pre-clinical models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

PlGF blockade does not inhibit angiogenesis during primary tumor growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Down-regulation of placenta growth factor by promoter hypermethylation in human lung and colon carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Neuropilins in neoplasms: expression, regulation, and function.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Intellectual and functional outcome of children 3 years old or younger who have CNS malignancies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Neuronal regulation of astroglial morphology and proliferation in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

VEGFR1-activity-independent metastasis formation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Second cancers after medulloblastoma: population-based results from the United States and Sweden

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Establishment and characterization of the human medulloblastoma cell line and transplantable xenograft D283 Med.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587980

alphaPlGF: a new kid on the antiangiogenesis block

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23452854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Monoclonal antibody TB-403: a first-in-human, Phase I, double-blind, dose escalation study directed against placental growth factor in healthy male subjects

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23452854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23452854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2013.01.036

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23452854

1 reference