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Novel functions of FoxM1: from molecular mechanisms to cancer therapy
scientific article published on 5 March 2013
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Europe PubMed Central
PMC publication ID
3588610
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
title
Novel functions of FoxM1: from molecular mechanisms to cancer therapy
(English)
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stated in
Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
author
Mónica Alvarez
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1
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Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
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25 February 2020
René H. Medema
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2
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Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
author name string
Mónica Alvarez-Fernández
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1
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Europe PubMed Central
PMC publication ID
3588610
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15 August 2017
publication date
5 March 2013
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Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
published in
Frontiers in Oncology
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stated in
Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
volume
3
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stated in
Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
page(s)
30
1 reference
stated in
Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
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FoxM1 inhibition sensitizes resistant glioblastoma cells to temozolomide by downregulating the expression of DNA-repair gene Rad51.
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Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA-damage
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A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis
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A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells
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PubMed Central
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30 September 2017
The transcription factor FOXM1 is a cellular target of the natural product thiostrepton
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
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30 September 2017
Protein phosphatase 2A (B55α) prevents premature activation of forkhead transcription factor FoxM1 by antagonizing cyclin A/cyclin-dependent kinase-mediated phosphorylation.
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Activation of nuclear factor-kappa B signalling promotes cellular senescence
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30 September 2017
Deregulation of FoxM1b leads to tumour metastasis
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30 September 2017
Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1.
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PubMed Central
reference URL
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30 September 2017
Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence
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PubMed Central
reference URL
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30 September 2017
Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes
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30 September 2017
FOXM1 confers acquired cisplatin resistance in breast cancer cells
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PubMed Central
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30 September 2017
Pro-proliferative FoxM1 is a target of p53-mediated repression
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30 September 2017
FoxM1, a critical regulator of oxidative stress during oncogenesis
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PubMed Central
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30 September 2017
FoxM1 is a general target for proteasome inhibitors
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PubMed Central
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30 September 2017
Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells
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PubMed Central
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30 September 2017
Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression
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PubMed Central
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30 September 2017
FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner
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30 September 2017
FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness
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30 September 2017
FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression.
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PubMed Central
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30 September 2017
Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain
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PubMed Central
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30 September 2017
The emerging roles of forkhead box (Fox) proteins in cancer
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30 September 2017
An N-terminal inhibitory domain modulates activity of FoxM1 during cell cycle
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PubMed Central
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30 September 2017
Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells
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PubMed Central
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30 September 2017
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
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30 September 2017
Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
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30 September 2017
Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1.
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30 September 2017
FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
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30 September 2017
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase
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PubMed Central
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30 September 2017
Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
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30 September 2017
FoxM1 is required for execution of the mitotic programme and chromosome stability
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
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30 September 2017
FOXM1 is a downstream target of Gli1 in basal cell carcinomas
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
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30 September 2017
Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification
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30 September 2017
The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization
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30 September 2017
The winged-helix transcription factor Trident is expressed in cycling cells
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30 September 2017
Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
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30 September 2017
FOXM1 coming of age: time for translation into clinical benefits?
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28 June 2018
The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia.
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
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28 June 2018
p53 negatively regulates expression of FoxM1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
retrieved
20 September 2018
DNA damage is able to induce senescence in tumor cells in vitro and in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3588610
retrieved
20 September 2018
Identifiers
DOI
10.3389/FONC.2013.00030
1 reference
stated in
Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
PMC publication ID
3588610
1 reference
stated in
Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
PubMed publication ID
23467617
1 reference
stated in
Europe PubMed Central
PMC publication ID
3588610
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23467617%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 February 2020
ResearchGate publication ID
235881701
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