(Q37893959)

24 August 2017

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title

Pro-senescence therapy for cancer treatment (English)

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24 August 2017

4

Pier Paolo Pandolfi

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John G Clohessy

object named as

John G Clohessy

series ordinal

2

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Caterina Nardella

series ordinal

1

object named as

Caterina Nardella

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24 August 2017

3

Andrea Alimonti

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24 August 2017

language of work or name

English

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publication date

24 June 2011

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24 August 2017

published in

Nature Reviews Cancer

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24 August 2017

volume

11

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24 August 2017

issue

7

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24 August 2017

page(s)

503-511

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https://scigraph.springernature.com/pub.10.1038/nrc3057

24 August 2017

exact match

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cites work

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Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

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Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

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Induction of senescence markers after neo-adjuvant chemotherapy of malignant pleural mesothelioma and association with clinical outcome: an exploratory analysis

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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31 March 2020

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c-Myc inhibition negatively impacts lymphoma growth

31 March 2020

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Pten dose dictates cancer progression in the prostate

31 March 2020

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Telomerase, Cell Immortality, and Cancer

31 March 2020

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Targeting the limitless replicative potential of cancer: the telomerase/telomere pathway

31 March 2020

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Telomerase and cancer therapeutics

31 March 2020

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Clinical significance of p53 alterations in surgically treated prostate cancers

31 March 2020

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Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors

31 March 2020

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The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence

31 March 2020

1 reference

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31 March 2020

1 reference

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.

31 March 2020

1 reference

12 December 2020

PML is induced by oncogenic ras and promotes premature senescence

1 reference

12 December 2020

Novel small molecule cyclin-dependent kinases modulators in human clinical trials

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12 December 2020

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

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12 December 2020

Tumor cell senescence in cancer treatment

1 reference

12 December 2020

Differential p53-independent outcomes of p19(Arf) loss in oncogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3057

1 reference

Dimensions Publication ID

24 August 2017

1026980068

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1 reference