(Q36659782)

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4-Aminobiphenyl and DNA reactivity: case study within the context of the 2006 IPCS Human Relevance Framework for Analysis of a cancer mode of action for humans.

scientific article published on November 2006

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scholarly article

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22 December 2019

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4-Aminobiphenyl and DNA reactivity: case study within the context of the 2006 IPCS Human Relevance Framework for Analysis of a cancer mode of action for humans (English)

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22 December 2019

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22 December 2019

R Julian Preston

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R Julian Preston

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22 December 2019

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Samuel M Cohen

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22 December 2019

M E Bette Meek

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22 December 2019

Douglas B McGregor

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22 December 2019

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1 November 2006

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22 December 2019

Critical Reviews in Toxicology

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22 December 2019

36

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22 December 2019

803-819

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22 December 2019

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22 December 2019

Quantitative immunohistochemical analysis of 4-aminobiphenyl-DNA in cultured cells and mice: comparison to gas chromatography/mass spectroscopy analysis

1 reference

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21 January 2018

Hemoglobin adducts of aromatic amines: associations with smoking status and type of tobacco

1 reference

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21 January 2018

DNA damage in human transitional cell carcinoma cells after exposure to the proximate metabolite of the bladder carcinogen 4-aminobiphenyl

1 reference

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21 January 2018

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

1 reference

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21 January 2018

Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer

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21 January 2018

Gender- and smoking-related bladder cancer risk

1 reference

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21 January 2018

Metabolic activation of the N-hydroxy derivative of the carcinogen 4-aminobiphenyl by human tissue sulfotransferases.

1 reference

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21 January 2018

CORRELATION BETWEEN THE CHEMICAL INDUCTION OF HYPERPLASIA AND OF MALIGNANCY IN THE BLADDER EPITHELIUM

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21 January 2018

The carcinogenic action of 2-aminodiphenylene oxide and 4-aminodiphenyl on the bladder and liver of the C57 X IF mouse

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21 January 2018

Role of urinary physiology and chemistry in bladder carcinogenesis

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21 January 2018

Mutagenicity of 4-aminobiphenyl and 4-acetylaminobiphenyl in Salmonella typhimurium strains expressing different levels of N-acetyltransferase.

1 reference

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21 January 2018

The non-carcinogenicity of a single dose of 4-aminobiphenyl in the dog.

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21 January 2018

Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vitro reaction of N-hydroxy-6-aminochrysene with DNA and the formation of these adducts in isolated rat hepatocytes treated with 6-nitrochr

1 reference

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21 January 2018

Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke

1 reference

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21 January 2018

N-hydroxy-4-aminobiphenyl-DNA binding in human p53 gene: sequence preference and the effect of C5 cytosine methylation

1 reference

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21 January 2018

4-Aminobiphenyl-DNA adducts in laryngeal tissue and smoking habits: an immunohistochemical study.

1 reference

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21 January 2018

Acetyl coenzyme A-dependent metabolic activation of N-hydroxy-3,2'-dimethyl-4-aminobiphenyl and several carcinogenic N-hydroxy arylamines in relation to tissue and species differences, other acyl donors, and arylhydroxamic acid-dependent acyltransfe

1 reference

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21 January 2018

DNA adduct levels in congenic rapid and slow acetylator mouse strains following chronic administration of 4-aminobiphenyl

1 reference

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21 January 2018

Acetyl transferase-mediated metabolic activation of N-hydroxy-4-aminobiphenyl by human uroepithelial cells

1 reference

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21 January 2018

Mutagenic activation of 4-aminobiphenyl and its N-hydroxy derivatives by microsomes from cultured human uroepithelial cells.

1 reference

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21 January 2018

Microsome-mediated transacetylation and binding of N-hydroxy-4-aminobiphenyl to nucleic acids by hepatic and bladder tissues from dog

1 reference

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21 January 2018

Detection of deoxyadenosine-4-aminobiphenyl adduct in DNA of human uroepithelial cells treated with N-hydroxy-4-aminobiphenyl following nuclease P1 enrichment and 32P-postlabeling analysis

1 reference

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21 January 2018

Identification of N-(deoxyguanosin-8-yl)-4-azobiphenyl by (32)P-postlabeling analyses of DNA in human uroepithelial cells exposed to proximate metabolites of the environmental carcinogen 4-aminobiphenyl

1 reference

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21 January 2018

The role of p53 and pRB in apoptosis and cancer

1 reference

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21 January 2018

Prostaglandin endoperoxide synthetase-mediated metabolism of carcinogenic aromatic amines and their binding to DNA and protein.

1 reference

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21 January 2018

CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice.

1 reference

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21 January 2018

CARCINOGENESIS IN THE HUMAN URINARY BLADDER: OBSERVATIONS AFTER EXPOSURE TO PARA-AMINODIPHENYL.

1 reference

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21 January 2018

Fifty years of research on N-acetyl-2-aminofluorene, one of the most versatile compounds in experimental cancer research.

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21 January 2018

Mechanism of peroxidative activation of the bladder carcinogen 2-amino-4-(5-nitro-2-furyl)-thiazole (ANFT): comparison with benzidine

1 reference

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21 January 2018

Altered Expression of Retinoblastoma Protein and Known Prognostic Variables in Locally Advanced Bladder Cancer

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21 January 2018

N-Acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark

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21 January 2018

The effects of genetic variation in N-acetyltransferases on 4-aminobiphenyl genotoxicity in mouse liver

1 reference

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21 January 2018

Analysis of the involvement of human N-acetyltransferase 1 in the genotoxic activation of bladder carcinogenic arylamines using a SOS/umu assay system

1 reference

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21 January 2018

Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression.

1 reference

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21 January 2018

Levels of 4-aminobiphenyl-induced somatic H-ras mutation in mouse liver DNA correlate with potential for liver tumor development

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21 January 2018

DNA adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for DNA adduct-based human cancer risk assessment.

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21 January 2018

DNA adduct formation and tumorigenesis in mice during the chronic administration of 4-aminobiphenyl at multiple dose levels.

1 reference

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21 January 2018

Quantitative assessments of the cytotoxicity of bladder carcinogens towards cultured normal human uroepithelial cells.

1 reference

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21 January 2018

Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism.

1 reference

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21 January 2018

Mutagenic outcome of the urinary carcinogen 4-aminobiphenyl is increased in acidic pH.

1 reference

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21 January 2018

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

1 reference

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21 January 2018

Bioactivation of xenobiotics by prostaglandin H synthase

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21 January 2018

IPCS conceptual framework for evaluating a mode of action for chemical carcinogenesis

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21 January 2018

Detection and characterization of carcinogen-DNA adducts in exfoliated urothelial cells from 4-aminobiphenyl-treated dogs by 32P-postlabelling and subsequent thin-layer and high-pressure liquid chromatography.

1 reference

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21 January 2018

4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice

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21 January 2018

Specificity of mutagenesis by 4-aminobiphenyl: mutations at G residues in bacteriophage M13 DNA and G-->C transversions at a unique dG(8-ABP) lesion in single-stranded DNA.

1 reference

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21 January 2018

Live or let die: the cell's response to p53

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21 January 2018

Immunohistochemical quantitation of 4-aminobiphenyl-DNA adducts and p53 nuclear overexpression in T1 bladder cancer of smokers and nonsmokers

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21 January 2018

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10.1080/10408440600977651

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17118730%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

Europe PubMed Central

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22 December 2019

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