(Q36673575)

15 August 2017

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title

Oxidative stress as a mechanism of valproic acid-associated hepatotoxicity (English)

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15 August 2017

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Thomas K H Chang

1

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15 August 2017

Frank S Abbott

series ordinal

2

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15 August 2017

language of work or name

English

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publication date

1 January 2006

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15 August 2017

published in

Drug Metabolism Reviews

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15 August 2017

volume

38

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15 August 2017

issue

4

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15 August 2017

page(s)

627-639

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Method to overcome photoreaction, a serious drawback to the use of dichlorofluorescin in evaluation of reactive oxygen species

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproic acid hepatic fatalities. III. U.S. experience since 1986.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Cytochrome C is a potent catalyst of dichlorofluorescin oxidation: implications for the role of reactive oxygen species in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Surveillance for fatal suspected adverse drug reactions in the UK

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Are we sure we know how to measure 8-oxo-7,8-dihydroguanine in DNA from human cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Early changes in hepatic redox homeostasis following treatment with a single dose of valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Isoprostanes as a biomarker of lipid peroxidation in humans: physiology, pharmacology and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproate-associated hepatotoxicity and its biochemical mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

The isoprostanes: unique products of arachidonic acid oxidation-a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Impaired mitochondrial function in microvesicular steatosis. Effects of drugs, ethanol, hormones and cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Reye-like syndrome associated with valproic acid therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Effects of age and polytherapy, risk factors of valproic acid (VPA) hepatotoxicity, on the excretion of thiol conjugates of (E)-2,4-diene VPA in people with epilepsy taking VPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Light-dependent generation of reactive oxygen species in cell culture media

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Blood levels of trace elements, electrolytes, and oxidative stress/antioxidant systems in epileptic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Mechanisms of liver injury. III. Role of glutathione redox status in liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Selenium, zinc, and copper changes with valproic acid: possible relation to drug side effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Metabolic activation of unsaturated derivatives of valproic acid. Identification of novel glutathione adducts formed through coenzyme A-dependent and -independent processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Evidence for a trigger function of valproic acid in xenobiotic-induced hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Fatal liver failure associated with valproate therapy in a patient with Friedreich's disease: review of valproate hepatotoxicity in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Severe hepatotoxicity during valproate therapy: an update and report of eight new fatalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Oxidative stress and electron spin resonance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproate-induced hepatic steatogenesis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Direct oxidation of 2',7'-dichlorodihydrofluorescein by pyocyanin and other redox-active compounds independent of reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Chemical depletion of glutathione in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

In vitro effects of valproate and valproate metabolites on mitochondrial oxidations. Relevance of CoA sequestration to the observed inhibitions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Biochemical basis of sodium valproate hepatotoxicity and renal tubular disorder: time dependence of peroxidative injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproic acid monotherapy induces DNA oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproate (VPA) metabolites in various clinical conditions of probable VPA-associated hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Fluorinated analogues as mechanistic probes in valproic acid hepatotoxicity: hepatic microvesicular steatosis and glutathione status

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

A single therapeutic dose of valproate affects liver carbohydrate, fat, adenylate, amino acid, coenzyme A, and carnitine metabolism in infant mice: possible clinical significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproic acid I: time course of lipid peroxidation biomarkers, liver toxicity, and valproic acid metabolite levels in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproic acid II: effects on oxidative stress, mitochondrial membrane potential, and cytotoxicity in glutathione-depleted rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Valproic acid glucuronidation is associated with increases in 15-F2t-isoprostane in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Serum copper, zinc, selenium, glutathione peroxidase and superoxide dismutase levels in epileptic children before and after 1 year of sodium valproate and carbamazepine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Role of metabolism in drug-induced idiosyncratic hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

Changes in the antioxidant system in epileptic children receiving antiepileptic drugs: two-year prospective studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530600959433

10.1080/03602530600959433

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference