(Q36673652)

15 August 2017

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title

Nucleic acid therapeutics for hematologic malignancies--theoretical considerations (English)

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15 August 2017

3

Jyoti Chattopadhyaya

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15 August 2017

Joanna B Opalinska

1

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15 August 2017

Anna Kalota

series ordinal

2

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15 August 2017

Masad Damha

series ordinal

4

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15 August 2017

Alan M Gewirtz

series ordinal

5

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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Annals of the New York Academy of Sciences

15 August 2017

published in

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15 August 2017

volume

1082

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15 August 2017

page(s)

124-136

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Research on resistance to cancer drug Gleevec

15 August 2017

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Cancer gene therapy: hard lessons and new courses

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Toward rules for 1:1 polyamide:DNA recognition

21 January 2018

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Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells

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Sequence-specific DNA recognition by polyamides

21 January 2018

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Nucleic-acid therapeutics: basic principles and recent applications

21 January 2018

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RNA interference for treating haematological malignancies

21 January 2018

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RNAi therapeutics: SNALPing siRNAs in vivo

21 January 2018

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A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H.

21 January 2018

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Ribozymes in the nucleolus

21 January 2018

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A general purpose RNA-cleaving DNA enzyme

21 January 2018

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Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes).

21 January 2018

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21 January 2018

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

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RNA interference as a gene-specific approach for molecular medicine

21 January 2018

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Biomembrane-permeable and Ribonuclease-resistant siRNA with enhanced activity

21 January 2018

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Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency.

21 January 2018

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

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Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

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siRNA binding proteins of microglial cells: PKR is an unanticipated ligand.

21 January 2018

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Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA.

21 January 2018

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Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology.

21 January 2018

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Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides

21 January 2018

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2'-O-[2-[(N,N-dimethylamino)oxy]ethyl]-modified oligonucleotides inhibit expression of mRNA in vitro and in vivo

21 January 2018

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Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules

21 January 2018

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Synthesis and Physicochemical Properties of 2′-Deoxy- 2′,2″-difluoro-β-D-ribofuranosyl and 2′-Deoxy-2′,2″- difluoro-α-D-ribofuranosyl Oligonucleotides

21 January 2018

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Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2'F-ANA constructs containing acyclic nucleotide inserts.

21 January 2018

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Identification of antisense nucleic acid hybridization sites in mRNA molecules with self-quenching fluorescent reporter molecules

21 January 2018

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Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells

21 January 2018

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Myb targeted therapeutics for the treatment of human malignancies

21 January 2018

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Role of the KIT protooncogene in normal and malignant human hematopoiesis

21 January 2018

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Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: a pilot study

21 January 2018

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The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene

21 January 2018

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Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias

21 January 2018

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Real time detection of DNA.RNA hybridization in living cells

21 January 2018

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Rationally targeted, conformationally constrained, oxetane-modified oligonucleotides demonstrate efficient gene-silencing activity in a cellular system

21 January 2018

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Entrapment of small molecules and nucleic acid-based drugs in liposomes

21 January 2018

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Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles

21 January 2018

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Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

21 January 2018

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Chitosan: some pharmaceutical and biological aspects--an update

21 January 2018

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Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

21 January 2018

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RNA accessibility prediction: a theoretical approach is consistent with experimental studies in cell extracts

21 January 2018

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21 January 2018

Does antisense exist?

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https://api.crossref.org/works/10.1196%2FANNALS.1348.002

RNAi: gene-silencing in therapeutic intervention

21 January 2018

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Fomivirsen - a phosphorothioate oligonucleotide for the treatment of CMV retinitis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1196/ANNALS.1348.002

1 reference

15 August 2017

1 reference