(Q36673663)

15 August 2017

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title

Anti-VEGF aptamer (pegaptanib) therapy for ocular vascular diseases (English)

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15 August 2017

Eugene W M Ng

1

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15 August 2017

Anthony P Adamis

series ordinal

2

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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Annals of the New York Academy of Sciences

15 August 2017

published in

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15 August 2017

volume

1082

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15 August 2017

page(s)

151-171

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Natural and engineered nucleic acids as tools to explore biology

15 August 2017

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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21 January 2018

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21 January 2018

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21 January 2018

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2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

21 January 2018

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Pharmacokinetics and biodistribution of novel aptamer compositions

21 January 2018

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Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

21 January 2018

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Vascular endothelial growth factor is a secreted angiogenic mitogen

21 January 2018

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VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

21 January 2018

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Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

21 January 2018

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Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor

21 January 2018

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Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

21 January 2018

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Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

21 January 2018

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Direct measurement of VEGF-induced nitric oxide production by choroidal endothelial cells

21 January 2018

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21 January 2018

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21 January 2018

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Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

21 January 2018

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VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection

21 January 2018

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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

21 January 2018

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Recombinant AAV vector encoding human VEGF165 enhances wound healing.

21 January 2018

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Single injections of vascular endothelial growth factor trap block ovulation in the macaque and produce a prolonged, dose-related suppression of ovarian function

21 January 2018

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Vascular endothelial growth factor-mediated, endothelium-dependent relaxation in human internal mammary artery

21 January 2018

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Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo

21 January 2018

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Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.

21 January 2018

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Role of growth factors and the wound healing response in age-related macular degeneration

21 January 2018

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Immunocytochemical localization of vascular endothelial growth factor in neurons and glial cells of human retina

21 January 2018

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Immunological and aetiological aspects of macular degeneration

21 January 2018

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Differential effects of light and alcohol on the electro-oculographic responses of patients with age-related macular disease

21 January 2018

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Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

21 January 2018

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

21 January 2018

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Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy

21 January 2018

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Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with diabetic macular edema and other retinal disorders

21 January 2018

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Expression of pigment epithelium derived factor and vascular endothelial growth factor in choroidal neovascular membranes and polypoidal choroidal vasculopathy

21 January 2018

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Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate

21 January 2018

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VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization.

21 January 2018

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A single local injection of recombinant VEGF receptor 2 but not of Tie2 inhibits retinal neovascularization in the mouse

21 January 2018

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Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF/flt-1 receptor gene transfection: a role of VEGF and possible treatment for SRN in age-related macular degeneration

21 January 2018

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An antisense oligodeoxynucleotide against vascular endothelial growth factor in a nonhuman primate model of iris neovascularization

21 January 2018

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Corticosteroids in posterior segment disease: an update on new delivery systems and new indications.

21 January 2018

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Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition

21 January 2018

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VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.

21 January 2018

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VEGF164Is Proinflammatory in the Diabetic Retina

21 January 2018

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Macrophage depletion inhibits experimental choroidal neovascularization

21 January 2018

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Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease

21 January 2018

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Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization

21 January 2018

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Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1.

21 January 2018

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Vitreal macrophages express vascular endothelial growth factor in oxygen-induced retinopathy.

21 January 2018

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Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo

21 January 2018

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Regression of neovascular age-related macular degeneration following infliximab therapy

21 January 2018

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An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

21 January 2018

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Causes and prevalence of visual impairment among adults in the United States

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1348.062

Pegaptanib for neovascular age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1348.062

Enhanced efficacy associated with early treatment of neovascular age-related macular degeneration with pegaptanib sodium: an exploratory analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1348.062

The prevalence of diabetic retinopathy among adults in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1348.062

Perspectives on diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1348.062

Vitrectomy in the management of diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1348.062

Early postoperative retinal thickness changes and complications after vitrectomy for diabetic macular edema

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1348.062

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1348.062

21 January 2018

Identifiers

DOI

10.1196/ANNALS.1348.062

1 reference

15 August 2017

1 reference