(Q36676071)

15 August 2017

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title

Chromatin modifications and DNA double-strand breaks: the current state of play (English)

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15 August 2017

Karagiannis TC

1

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15 August 2017

El-Osta A

series ordinal

2

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15 August 2017

publication date

7 December 2006

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15 August 2017

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15 August 2017

volume

21

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15 August 2017

issue

2

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15 August 2017

page(s)

195-200

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Sensing and repairing DNA double-strand breaks

15 August 2017

cites work

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DNA double-strand breaks: signaling, repair and the cancer connection

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Mechanism and regulation of human non-homologous DNA end-joining

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ATM, a central controller of cellular responses to DNA damage.

21 January 2018

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Mechanisms of eukaryotic DNA double strand break repair

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The role of double-strand break repair — insights from human genetics

21 January 2018

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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

21 January 2018

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Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

21 January 2018

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Homologous DNA recombination in vertebrate cells

21 January 2018

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Homologous recombinational repair of DNA ensures mammalian chromosome stability

21 January 2018

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21 January 2018

Human DNA repair genes

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Topography of the histone octamer surface: repeating structural motifs utilized in the docking of nucleosomal DNA

21 January 2018

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Crystal structure of the nucleosome core particle at 2.8 A resolution

21 January 2018

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Molecular biology. Chromatin higher order folding--wrapping up transcription

21 January 2018

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Histone variants: deviants?

21 January 2018

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Chromatin remodelling: the industrial revolution of DNA around histones

21 January 2018

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Functional consequences of histone modifications

21 January 2018

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An increasingly complex code

21 January 2018

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

21 January 2018

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Active role for nibrin in the kinetics of atm activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

21 January 2018

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

21 January 2018

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Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

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H2AX: the histone guardian of the genome

21 January 2018

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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 January 2018

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MDC1 is required for the intra-S-phase DNA damage checkpoint

21 January 2018

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MDC1 is a mediator of the mammalian DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Genomic instability in mice lacking histone H2AX

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Characteristics of gamma-H2AX foci at DNA double-strand breaks sites

21 January 2018

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ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Complicated tails: histone modifications and the DNA damage response

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break

21 January 2018

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DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis

21 January 2018

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Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions

21 January 2018

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The histone code at DNA breaks: a guide to repair?

21 January 2018

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Control of sister chromatid recombination by histone H2AX.

21 January 2018

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Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

21 January 2018

1 reference

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gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

21 January 2018

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A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

21 January 2018

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ATP-dependent chromatin remodeling and DNA double-strand break repair.

21 January 2018

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INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

21 January 2018

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Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair

21 January 2018

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Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites

21 January 2018

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Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

21 January 2018

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ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex

21 January 2018

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A chromatin remodelling complex involved in transcription and DNA processing.

21 January 2018

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A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Genes required for ionizing radiation resistance in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

ATP-dependent and ATP-independent roles for the Rad54 chromatin remodeling enzyme during recombinational repair of a DNA double strand break

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Rad54p is a chromatin remodeling enzyme required for heteroduplex DNA joint formation with chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Rad54 protein possesses chromatin-remodeling activity stimulated by the Rad51-ssDNA nucleoprotein filament

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Strand pairing by Rad54 and Rad51 is enhanced by chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

NuA4 subunit Yng2 function in intra-S-phase DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Phosphorylation of histone H2B at DNA double-strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Gene silencing: trans-histone regulatory pathway in chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

Abundance of the RSC nucleosome-remodeling complex is important for the cells to tolerate DNA damage in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

inferred from DOI database lookup

7 January 2021

based on heuristic

A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404478

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.LEU.2404478

1 reference

15 August 2017

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