(Q36686933)

15 August 2017

1 reference

title

Modulation of ionotropic GABA receptors by natural products of plant origin (English)

1 reference

15 August 2017

1 reference

Graham A R Johnston

1

1 reference

15 August 2017

Jane R Hanrahan

2

1 reference

15 August 2017

Mary Chebib

3

1 reference

15 August 2017

Rujee K Duke

4

1 reference

15 August 2017

Kenneth N Mewett

5

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15 August 2017

publication date

1 January 2006

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15 August 2017

published in

Advances in Pharmacology

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15 August 2017

volume

54

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15 August 2017

page(s)

285-316

1 reference

Dietary flavonols: chemistry, food content, and metabolism

15 August 2017

cites work

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7 January 2021

Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro

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7 January 2021

Sex differences in the effects of gonadectomy and acute swim stress on GABAA receptor binding in mouse forebrain membranes

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7 January 2021

Low doses of ethanol and a neuroactive steroid positively interact to modulate rat GABA(A) receptor function

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7 January 2021

Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla

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7 January 2021

Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons

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7 January 2021

Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors

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7 January 2021

Inhibition of benzodiazepine binding in vitro by amentoflavone, a constituent of various species of Hypericum

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7 January 2021

GABA in plants: just a metabolite?

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7 January 2021

GABA signaling: a conserved and ubiquitous mechanism

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7 January 2021

Effects of single intraperitoneal injections of an extract of Ginkgo biloba (EGb 761) and its terpene trilactone constituents on barbital-induced narcosis in the mouse

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7 January 2021

Plant foods and herbal sources of resveratrol

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7 January 2021

In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs

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7 January 2021

The dietary flavonoids apigenin and (-)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABA(A) receptors

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7 January 2021

Structure-activity relationship of miltirone, an active central benzodiazepine receptor ligand isolated from Salvia miltiorrhiza Bunge (Danshen).

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7 January 2021

Structure-activity studies with Ginkgo biloba extract constituents as receptor-gated chloride channel blockers and modulators

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7 January 2021

GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology

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7 January 2021

Effects of ginsenosides on GABA(A) receptor channels expressed in Xenopus oocytes

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7 January 2021

Protective effect of epigallocatechin gallate on brain damage after transient middle cerebral artery occlusion in rats

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7 January 2021

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

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7 January 2021

Effect of a polyacetylenic fish poison on the oxidative phosphorylation of rat liver mitochondria

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7 January 2021

Bicuculline and Central GABA Receptors

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7 January 2021

Bilobalide and neuroprotection

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7 January 2021

Alpha-thujone reduces 5-HT3 receptor activity by an effect on the agonist-reduced desensitization

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7 January 2021

Valerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitro

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7 January 2021

Sedative and anticonvulsant activities of goodyerin, a flavonol glycoside from Goodyera schlechtendaliana

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis

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7 January 2021

3-Hydroxy-4,5-dimethyl-2(5H)-furanone: a key odorant of the typical aroma of oxidative aged Port wine

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7 January 2021

Neurotrophic activity of honokiol on the cultures of fetal rat cortical neurons

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7 January 2021

Opposing roles for GABAA and GABAC receptors in short-term memory formation in young chicks

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7 January 2021

GABA mechanisms and sleep

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Flavonoid modulation of ionic currents mediated by GABA(A) and GABA(C) receptors

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

(+)- And (-)-borneol: efficacious positive modulators of GABA action at human recombinant alpha1beta2gamma2L GABA(A) receptors

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7 January 2021

Transport of amentoflavone across the blood-brain barrier in vitro

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Modulation of radioligand binding to the GABA(A)-benzodiazepine receptor complex by a new component from Cyperus rotundus

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors.

1 reference

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7 January 2021

Alcohol effects on gamma-aminobutyric acid type A receptors: are extrasynaptic receptors the answer?

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7 January 2021

Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors

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7 January 2021

Transfected cells for study of alcohol actions on GABA(A) receptors

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7 January 2021

The biochemistry and medical significance of the flavonoids

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7 January 2021

Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships

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7 January 2021

Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification

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7 January 2021

Decreased binding of [11C]flumazenil in Angelman syndrome patients with GABA(A) receptor beta3 subunit deletions

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7 January 2021

Potentiation of the ionotropic GABA receptor response by whiskey fragrance

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7 January 2021

Effects of tea components on the response of GABA(A) receptors expressed in Xenopus Oocytes

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7 January 2021

Effects of coffee components on the response of GABA(A) receptors expressed in Xenopus oocytes

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7 January 2021

Fragrances in oolong tea that enhance the response of GABAA receptors

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7 January 2021

Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, is an antagonist at recombinant alpha1beta2gamma2L GABA(A) receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1beta2gamma2L GABAA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Mixed antagonistic effects of bilobalide at rho1 GABAC receptor

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Naturally occurring 2'-hydroxyl-substituted flavonoids as high-affinity benzodiazepine site ligands

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

5,7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

An anxiolytic agent, dihydrohonokiol-B, inhibits ammonia-induced increases in the intracellular Cl(-) of cultured rat hippocampal neurons via GABA(c) receptors

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Interactions of flavones and other phytochemicals with adenosine receptors

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Structural aspects of picrotoxinin action

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

GABAA receptor pharmacology

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7 January 2021

GABA(A) receptor channel pharmacology

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7 January 2021

Flavonoids: some of the wisdom of sage?

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7 January 2021

Central actions of ibotenic acid and muscimol

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7 January 2021

GABA(C) receptors as drug targets

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7 January 2021

Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression.

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7 January 2021

Effects of bilobalide on amino acid release and electrophysiology of cortical slices

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7 January 2021

GABA(A) receptor function and pharmacology in epilepsy and status epilepticus.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Constituents of sage (Salvia officinalis) with in vitro affinity to human brain benzodiazepine receptor

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7 January 2021

The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects

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7 January 2021

Epigallocatechin gallate induces apoptosis of monocytes

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7 January 2021

Aging of whiskey increases the potentiation of GABA(A) receptor response

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7 January 2021

Comparative assessment of the anxiolytic-like activities of honokiol and derivatives.

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7 January 2021

Mechanisms of Cancer Prevention by Tea Constituents

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7 January 2021

Cancer preventive effects of flavonoids--a review

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7 January 2021

The Ligand Gated Ion Channel database: an example of a sequence database in neuroscience

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7 January 2021

Miltirone, a central benzodiazepine receptor partial agonist from a Chinese medicinal herb Salvia miltiorrhiza.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

(-)-Epigallocatechin gallate attenuates glutamate-induced cytotoxicity via intracellular Ca modulation in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Honokiol ameliorates cerebral infarction from ischemia-reperfusion injury in rats

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Anxiolytic agent, dihydrohonokiol-B, recovers amyloid beta protein-induced neurotoxicity in cultured rat hippocampal neurons

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Apigenin modulates GABAergic and glutamatergic transmission in cultured cortical neurons

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

The mechanism of honokiol-induced and magnolol-induced inhibition on muscle contraction and Ca2+ mobilization in rat uterus.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Isolation and Identification of "Diazepam-Like" Compounds From Bovine Urine

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

GABA(A)-receptor ligands of flavonoid structure

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Which GABAA-receptor subtypes really occur in the brain?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Overview--flavonoids: a new family of benzodiazepine receptor ligands.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Modern drug development from traditional medicinal plants using radioligand receptor-binding assays

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Structural requirements of phenol derivatives for direct activation of chloride currents via GABA(A) receptors

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Attenuation of stress-induced elevations in plasma ACTH level and body temperature in rats by green odor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

High affinity of the naturally-occurring biflavonoid, amentoflavon, to brain benzodiazepine receptors in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

GABA(A) receptor changes in delta subunit-deficient mice: altered expression of alpha4 and gamma2 subunits in the forebrain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Medicinal plants and Alzheimer's disease: from ethnobotany to phytotherapy

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Essential oils from dalmatian sage (Salvia officinalis l.): variations among individuals, plant parts, seasons, and sites

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Picrotoxin accelerates relaxation of GABAC receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Isolation and identification from Salvia officinalis of two diterpenes which inhibit t-butylbicyclophosphoro[35S]thionate binding to chloride channel of rat cerebrocortical membranes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Effects of bilobalide on gamma-aminobutyric acid levels and glutamic acid decarboxylase in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Diazepam enhancement of low affinity GABA binding to rat brain membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Reduced inhibition and sensitivity to neurosteroids in hippocampus of mice lacking the GABA(A) receptor delta subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

The "French Paradox" and beyond: neuroprotective effects of polyphenols

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Preferential coassembly of alpha4 and delta subunits of the gamma-aminobutyric acidA receptor in rat thalamus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Exploring the structural basis of neurotoxicity in C(17)-polyacetylenes isolated from water hemlock

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Virol A, a toxic trans-polyacetylenic alcohol of Cicuta virosa, selectively inhibits the GABA-induced Cl(-) current in acutely dissociated rat hippocampal CA1 neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Heritable mutations in the glycine, GABAA, and nicotinic acetylcholine receptors provide new insights into the ligand-gated ion channel receptor superfamily.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Mutant GABA(A) receptor gamma2-subunit in childhood absence epilepsy and febrile seizures

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Benzodiazepines act on GABAA receptors via two distinct and separable mechanisms.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Structure-activity relationships of flavonoids, isolated from Scutellaria baicalensis, binding to benzodiazepine site of GABA(A) receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABA(A) receptors, from Valeriana wallichii.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Studies on the Active Principle of Mangolia Bark. Centrally Acting Muscle Relaxant Activity of Mangolol and Hönokiol

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Pharmacological properties of magnolol and honokiol extracted from Magnolia officinalis: central depressant effects

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Vascular and anti-oxidant actions of flavonols and flavones.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

GABAC receptor agonist suppressed ammonia‐induced apoptosis in cultured rat hippocampal neurons by restoring phosphorylated BAD level

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

GABA, a new player in the plant mating game

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Steroid hormone activity of flavonoids and related compounds.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

Behavioral characterisation of the flavonoids apigenin and chrysin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954012-8

7 January 2021

10.1016/S1054-3589(06)54012-8

Identifiers

DOI

1 reference

15 August 2017

1 reference