(Q36689081)

English

Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump

scientific article published on January 2007

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

1 reference

Europe PubMed Central

Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

0 references

intrahepatic cholestasis

1 reference

based on heuristic

inferred from title

Toshihisa Ishikawa

5

object named as

Toshihisa Ishikawa

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

author name string

Aki Sakurai

1

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Atsuo Kurata

2

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Yuko Onishi

3

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Hiroyuki Hirano

4

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

language of work or name

0 references

publication date

1 January 2007

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Expert Opinion on Drug Safety

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

71-86

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The ATP-dependent glutathione S-conjugate export pump

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Mechanisms and regulation of bile secretion

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile salt transporters: molecular characterization, function, and regulation

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Enterohepatic bile salt transporters in normal physiology and liver disease

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile acid regulation of hepatic physiology: IV. Bile acids and death receptors

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile salt transporters

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Hepatic transport of bile salts

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Identification of a ligand-binding site in the Na+/bile acid cotransporting protein from rabbit ileum

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile acid regulation of hepatic physiology: I. Hepatocyte transport of bile acids

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile salt excretory pump: biology and pathobiology

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile acid regulation of hepatic physiology: III. Bile acids and nuclear receptors

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Mammalian ABC transporters in health and disease

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The bile salt export pump: molecular properties, function and regulation

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Functional expression of the canalicular bile salt export pump of human liver

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

A patient with novel ABCB11 gene mutations with phenotypic transition between BRIC2 and PFIC2.

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver.

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile Salt Export Pump Gene Mutations in Two Japanese Patients With Progressive Familial Intrahepatic Cholestasis

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Benign recurrent intrahepatic cholestasis associated with mutations of the bile salt export pump.

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Hepatobiliary transporters and drug-induced cholestasis

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Characterization of the mouse bile salt export pump overexpressed in the baculovirus system

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Potential cholestatic activity of various therapeutic agents assessed by bile canalicular membrane vesicles isolated from rats and humans

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The human bile salt export pump: characterization of substrate specificity and identification of inhibitors

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

High-speed screening of human ATP-binding cassette transporter function and genetic polymorphisms: new strategies in pharmacogenomics.

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Pharmacogenomics of drug transporters: a new approach to functional analysis of the genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1).

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Functional evaluation of ABCB1 (P-glycoprotein) polymorphisms: high-speed screening and structure-activity relationship analyses

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

A new strategy of high-speed screening and quantitative structure-activity relationship analysis to evaluate human ATP-binding cassette transporter ABCG2-drug interactions

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Metabolic and non-metabolic factors determining troglitazone hepatotoxicity: a review

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Mechanisms of troglitazone hepatotoxicity

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

The role of metabolic activation in drug-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Idiosyncratic drug hepatotoxicity

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

NIH Molecular Libraries Initiative

1 reference

https://api.crossref.org/works/10.1517%2F14740338.6.1.71

21 January 2018

Identifiers

10.1517/14740338.6.1.71

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36689081&oldid=1672501434"