(Q36691546)

15 August 2017

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title

p16 and p27 are functionally correlated during the progress of hepatocarcinogenesis (English)

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15 August 2017

Yasunobu Matsuda

1

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PubMed ID

17187177

15 August 2017

Takafumi Ichida

series ordinal

2

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15 August 2017

21 December 2006

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Medical Molecular Morphology

15 August 2017

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15 August 2017

39

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15 August 2017

4

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15 August 2017

169-175

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https://scigraph.springernature.com/pub.10.1007/s00795-006-0339-2

15 August 2017

0 references

cites work

p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers

1 reference

https://api.crossref.org/works/10.1007%2FS00795-006-0339-2

Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00795-006-0339-2

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00795-006-0339-2

Overall survival in aggressive B-cell lymphomas is dependent on the accumulation of alterations in p53, p16, and p27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00795-006-0339-2

Expression and prognostic roles of the G1-S modulators in hepatocellular carcinoma: p27 independently predicts the recurrence

21 January 2018

1 reference

12 December 2020

Anomalous high p27/KIP1 expression in a subset of aggressive B-cell lymphomas is associated with cyclin D3 overexpression. p27/KIP1-cyclin D3 colocalization in tumor cells.

1 reference

12 December 2020

Regulation of the cdk inhibitor p27 and its deregulation in cancer

1 reference

12 December 2020

Mutational study of p16CDKN2/MTS1/INK4A and p57KIP2 genes in hepatocellular carcinoma

1 reference

12 December 2020

Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus

1 reference

12 December 2020

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 reference

12 December 2020

Inactivation of p16INK4 in hepatocellular carcinoma

1 reference

12 December 2020

p16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma

1 reference

12 December 2020

High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

1 reference

12 December 2020

New functional activities for the p21 family of CDK inhibitors

1 reference

12 December 2020

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

12 December 2020

Loss of p16 contributes to p27 sequestration by cyclin D(1)-cyclin-dependent kinase 4 complexes and poor prognosis in hepatocellular carcinoma.

1 reference

12 December 2020

p16INK4A hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma.

1 reference

12 December 2020

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1 reference

12 December 2020

Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma

1 reference

12 December 2020

Mechanisms of Human Hepatocarcinogenesis

1 reference

12 December 2020

Deregulated expression of p27(Kip1) in human breast cancers.

1 reference

12 December 2020

Hepatocellular carcinoma

1 reference

12 December 2020

Multiple functions of p27(Kip1) and its alterations in tumor cells: a review

1 reference

12 December 2020

Overexpressed Id-1 is associated with a high risk of hepatocellular carcinoma development in patients with cirrhosis without transcriptional repression of p16

1 reference

12 December 2020

Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinoma

1 reference

12 December 2020

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

12 December 2020

Inhibition of cell growth and induction of G1-phase cell cycle arrest in hepatoma cells by steroid extract from Meretrix meretrix

1 reference

12 December 2020

Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

1 reference

12 December 2020

Localization and expression of p27KIP1 in multistage colorectal carcinogenesis

1 reference

12 December 2020

Infrequent alterations of the p16INK4A gene in liver cancer

1 reference

12 December 2020

Genetic mechanisms of hepatocarcinogenesis

1 reference

12 December 2020

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

12 December 2020

Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells

1 reference

12 December 2020

10.1007/S00795-006-0339-2

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17187177