(Q40398127)

English

Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells

scientific article published on 13 July 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

author name string

Junhong Han

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Yu-ichi Tsukada

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Eiji Hara

3

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Naomi Kitamura

4

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Toshiaki Tanaka

5

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

language of work or name

0 references

publication date

13 July 2005

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

280

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

36

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

31548-31556

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Molecular aspects of mesenchymal-epithelial interactions

1 reference

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Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

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21 January 2018

Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor

1 reference

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21 January 2018

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

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21 January 2018

Molecular cloning and expression of human hepatocyte growth factor

1 reference

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Properties and functions of scatter factor/hepatocyte growth factor and its receptor c-Met

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The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis

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Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction

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Scatter factor/hepatocyte growth factor is essential for liver development

1 reference

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Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

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A fibroblast-derived tumor cytotoxic factor/F-TCF(hepatocyte growth factor/HGF) has multiple functions in vitro

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Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells

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Hepatocyte growth factor has potent anti-proliferative activity in various tumor cell lines

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Hepatocyte growth factor/scatter factor modulates intestinal epithelial cell proliferation and migration

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Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 tran

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Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: cloning of its cDNA, purification and characterization of recombinant protein

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Regulation of cell growth and motility by hepatocyte growth factor and receptor expression in various cell species

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Hepatocyte growth factor inhibits cell proliferation in vivo of rat hepatocellular carcinomas induced by diethylnitrosamine

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Inhibition of neoplastic development in the liver by hepatocyte growth factor in a transgenic mouse model

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Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

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21 January 2018

The human met oncogene is related to the tyrosine kinase oncogenes

1 reference

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21 January 2018

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

1 reference

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21 January 2018

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

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21 January 2018

HGF/SF-met signaling in the control of branching morphogenesis and invasion

1 reference

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21 January 2018

High intensity ERK signal mediates hepatocyte growth factor-induced proliferation inhibition of the human hepatocellular carcinoma cell line HepG2.

1 reference

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21 January 2018

Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.

1 reference

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21 January 2018

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

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21 January 2018

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

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21 January 2018

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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21 January 2018

Direct evidence from siRNA-directed "knock down" that p16(INK4a) is required for human fibroblast senescence and for limiting ras-induced epithelial cell proliferation

1 reference

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21 January 2018

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

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21 January 2018

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

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21 January 2018

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

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21 January 2018

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4

1 reference

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21 January 2018

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

1 reference

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21 January 2018

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

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The INK4a/ARF network in tumour suppression

1 reference

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The RB and p53 pathways in cancer

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ETS transcription factors: possible targets for cancer therapy

1 reference

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21 January 2018

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

1 reference

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21 January 2018

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

1 reference

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21 January 2018

Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment

1 reference

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Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway

1 reference

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A Raf/MEK/ERK signaling pathway is required for development of the sea urchin embryo micromere lineage through phosphorylation of the transcription factor Ets.

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The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity

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Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

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Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)

1 reference

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The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

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Cooperation of p27(Kip1) and p18(INK4c) in progestin-mediated cell cycle arrest in T-47D breast cancer cells.

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Cooperating oncogenes converge to regulate cyclin/cdk complexes.

1 reference

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High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

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Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway

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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

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Inhibition of cyclin-dependent kinases by p21

1 reference

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Ink4a/Arf expression is a biomarker of aging

1 reference

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Identifiers

10.1074/JBC.M503431200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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