(Q40525768)

21 September 2017

title

The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity (English)

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21 September 2017

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Calbó J

1

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21 September 2017

Serna C

2

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21 September 2017

Garriga J

3

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21 September 2017

Graña X

4

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21 September 2017

Mazo A

5

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21 September 2017

publication date

1 October 2004

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Cell Death & Differentiation

21 September 2017

published in

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21 September 2017

volume

11

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21 September 2017

issue

10

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21 September 2017

page(s)

1055-1065

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401481

21 September 2017

exact match

0 references

cites work

Brief report: a familial syndrome of pancreatic cancer and melanoma with a mutation in the CDKN2 tumor-suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Growth suppression by p16ink4 requires functional retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Induction of apoptosis in p16INK4A mutant cell lines by adenovirus-mediated overexpression of p16INK4A protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Adenovirus-mediated gene transfer of P16INK4/CDKN2 into bax-negative colon cancer cells induces apoptosis and tumor regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Adenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Differential regulation of the retinoblastoma family of proteins during cell proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Phosphorylation site specificity of the CDC2-related kinase PITALRE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

E1A blocks hyperphosphorylation of p130 and p107 without affecting the phosphorylation status of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Proliferation of cancer cells despite CDK2 inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

p21Waf1/Cip1 as a therapeutic target in breast and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

pRB Contains an E2F1-Specific Binding Domain that Allows E2F1-Induced Apoptosis to Be Regulated Separately from Other E2F Activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

Requirements for cell cycle arrest by p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Down-regulation of bcl-2 is associated with p16INK4-mediated apoptosis in non-small cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Use of recombinant adenovirus for metabolic engineering of mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Cdk2-dependent phosphorylation and functional inactivation of the pRB-related p130 protein in pRB(-), p16INK4A(+) tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

E1A modulates phosphorylation of p130 and p107 by differentially regulating the activity of G1/S cyclin/CDK complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Cyclin E in human cancers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401481

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401481

1 reference

Dimensions Publication ID

21 September 2017

1006882457

0 references

1 reference