(Q43785744)

26 November 2017

Adenovirus-mediated wt-p16 reintroduction induces cell cycle arrest or apoptosis in pancreatic cancer (English)

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26 November 2017

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5

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26 November 2017

Calbó J

1

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26 November 2017

Marotta M

2

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26 November 2017

Cascalló M

3

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26 November 2017

Roig JM

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26 November 2017

Fueyo J

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26 November 2017

Mazo A

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26 November 2017

1 October 2001

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26 November 2017

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26 November 2017

8

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26 November 2017

740-750

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26 November 2017

10

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https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700374

26 November 2017

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Cancer statistics, 1998.

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7 January 2021

Novel clinical strategies for the treatment of pancreatic carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Gene therapy for cancer: what have we done and where are we going?

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Gene therapy for cancer

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7 January 2021

Cancer gene therapy: hard lessons and new courses

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Cell cycle and apoptosis: common pathways to life and death.

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Gene therapy for cancer

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Cell death and cancer: replacement of apoptotic genes and inactivation of death suppressor genes in therapy

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

The INK4a/ARF tumor suppressor: one gene--two products--two pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

mdm2: a bridge over the two tumour suppressors, p53 and Rb.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Induction of senescence in human malignant glioma cells by p16INK4A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Adenoviral vector containing wild-type p16 suppresses prostate cancer growth and prolongs survival by inducing cell senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

p16INK4 mediates contact-inhibition of growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Modulation of drug cytotoxicity by reintroduction of wild-type p53 gene (Ad5CMV-p53) in human pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Use of recombinant adenovirus for metabolic engineering of mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

The potential for gene therapy in pancreatic cancer

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Strategies for targeting therapeutic gene delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

The retinoblastoma protein pathway in cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Down-regulation of bcl-2 is associated with p16INK4-mediated apoptosis in non-small cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Expression of p16 induces transcriptional downregulation of the RB gene

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

E2F-1-induced p53-independent apoptosis in transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

p16/MTS1/INK4A suppresses prostate cancer by both pRb dependent and independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700374

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700374

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Dimensions Publication ID

26 November 2017

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