(Q36701461)

English

Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition

scientific article published on August 2004

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

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inferred from title

Robert G Hawley

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Robert G Hawley

4

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John E Dick

5

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author name string

Craig Dorrell

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Katsuto Takenaka

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Mark D Minden

3

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Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

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publication date

1 August 2004

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Europe PubMed Central

PMC publication ID

15 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

15 August 2017

24

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Europe PubMed Central

PMC publication ID

15 August 2017

16

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

6993-7002

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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1 reference

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1 reference

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Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner

1 reference

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Ras and relatives--job sharing and networking keep an old family together

1 reference

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Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line

1 reference

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30 September 2017

Stem cells, cancer, and cancer stem cells

1 reference

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High intensity ERK signal mediates hepatocyte growth factor-induced proliferation inhibition of the human hepatocellular carcinoma cell line HepG2.

1 reference

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The farnesyl transferase inhibitor SCH 66336 induces a G(2) --> M or G(1) pause in sensitive human tumor cell lines

1 reference

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1 reference

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Mutant RAS inhibits neutrophil but not macrophage differentiation and allows continued growth of neutrophil precursors

1 reference

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Ras proteins: recent advances and new functions.

1 reference

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

1 reference

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Signaling specificity: the RTK/RAS/MAP kinase pathway in metazoans

1 reference

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Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation

1 reference

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30 September 2017

Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells

1 reference

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Involvement of H-ras in erythroid differentiation of TF1 and human umbilical cord blood CD34 cells

1 reference

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Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo

1 reference

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K-ras is an essential gene in the mouse with partial functional overlap with N-ras

1 reference

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30 September 2017

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

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30 September 2017

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

1 reference

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30 September 2017

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

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30 September 2017

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

1 reference

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30 September 2017

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

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Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells

1 reference

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What is ineffective erythropoiesis in myelodysplastic syndromes?

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes

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ras oncogenes in human cancer: a review

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Mutant ras promotes haemopoietic cell proliferation or differentiation in a cell-specific manner.

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1 reference

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Identifiers

10.1128/MCB.24.16.6993-7002.2004

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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