(Q36709542)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

review article

1 reference

title

MTP inhibition as a treatment for dyslipidaemias: time to deliver or empty promises? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

John R Burnett

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

English

0 references

publication date

1 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

24 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

181-189

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

Apolipoproteins versus lipids as indices of coronary risk and as targets for statin treatment

24 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Apolipoproteins as markers and managers of coronary risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Recent studies of lipoprotein kinetics in the metabolic syndrome and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Diabetic dyslipidaemia: from basic research to clinical practice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Complete protein sequence and identification of structural domains of human apolipoprotein B

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Functional analysis of disulfide linkages clustered within the amino terminus of human apolipoprotein B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

A common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Human microsomal triglyceride transfer protein large subunit gene structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Microsomal triglyceride transfer protein: a multifunctional protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Apolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: roles of MAPKerk and MAPKp38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Apo B100-containing lipoproteins are secreted by the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Lipoprotein secretion and triglyceride stores in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Achieving and maintaining National Cholesterol Education Program low-density lipoprotein cholesterol goals with five statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Molecular and metabolic basis for the metabolic disorder normotriglyceridemic abetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Monogenic hypocholesterolaemic lipid disorders and apolipoprotein B metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

The role of the microsomal triglygeride transfer protein in abetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

A 30-amino acid truncation of the microsomal triglyceride transfer protein large subunit disrupts its interaction with protein disulfide-isomerase and causes abetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Current biology of MTP: implications for selective inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Liver dysfunction and steatosis in familial hypobetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Lipid disorders and mutations in the APOB gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Inhibition of Net HepG2 Cell Apolipoprotein B Secretion by the Citrus Flavonoid Naringenin Involves Activation of Phosphatidylinositol 3-Kinase, Independent of Insulin Receptor Substrate-1 Phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Naringenin 7-O-cetyl ether as inhibitor of HMG-CoA reductase and modulator of plasma and hepatic lipids in high cholesterol-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Evaluation of hesperetin 7-O-lauryl ether as lipid-lowering agent in high-cholesterol-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Naringenin derivatives as anti-atherogenic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Antisense oligonucleotides as therapeutics for hyperlipidaemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Therapeutic potential of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and secretion of apolipoprotein B lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.2.181

10.1517/14728222.11.2.181

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17227233%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference