(Q36726792)

15 August 2017

Alternative transcription initiation leads to expression of a novel ALK isoform in cancer (English)

1 reference

15 August 2017

11

1 reference

15 August 2017

28

Marc Ladanyi

1 reference

15 August 2017

Shipra Shukla

18

0 references

Travis J. Hollmann

Travis J Hollmann

19

0 references

Dong Gao

Dong Gao

15

0 references

Anna C Obenauf

Anna C Obenauf

3

0 references

Ronak H Shah

Ronak H Shah

10

0 references

Thomas Wiesner

Thomas Wiesner

1

0 references

Deyou Zheng

Deyou Zheng

27

0 references

Rajmohan Murali

Rajmohan Murali

5

0 references

author name string

William Lee

2

1 reference

15 August 2017

Leili Ran

4

1 reference

15 August 2017

Qi Fan Zhang

6

1 reference

15 August 2017

Elissa W P Wong

7

1 reference

15 August 2017

Wenhuo Hu

8

1 reference

15 August 2017

Sasinya N Scott

9

1 reference

15 August 2017

Julia Button

12

1 reference

15 August 2017

Nathalie Lailler

13

1 reference

15 August 2017

Andrea Sboner

14

1 reference

15 August 2017

Devan A Murphy

16

1 reference

15 August 2017

Zhen Cao

17

1 reference

15 August 2017

Lu Wang

20

1 reference

15 August 2017

Laetitia Borsu

21

1 reference

15 August 2017

Taha Merghoub

22

1 reference

15 August 2017

Gary K Schwartz

23

1 reference

15 August 2017

Michael A Postow

24

1 reference

15 August 2017

Charlotte E Ariyan

25

1 reference

15 August 2017

James A Fagin

26

1 reference

15 August 2017

Klaus J Busam

29

1 reference

15 August 2017

Michael F Berger

30

1 reference

15 August 2017

Yu Chen

31

1 reference

15 August 2017

Ping Chi

32

1 reference

15 August 2017

language of work or name

English

0 references

publication date

7 October 2015

1 reference

15 August 2017

1 reference

15 August 2017

526

1 reference

15 August 2017

7573

1 reference

15 August 2017

453-457

1 reference

https://scigraph.springernature.com/pub.10.1038/nature15258

15 August 2017

0 references

cites work

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Detecting somatic genetic alterations in tumor specimens by exon capture and massively parallel sequencing.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

The Genotype-Tissue Expression (GTEx) project

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Modification of enhancer chromatin: what, how, and why?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

DELLY: structural variant discovery by integrated paired-end and split-read analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Detecting differential usage of exons from RNA-seq data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

CREST maps somatic structural variation in cancer genomes with base-pair resolution.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

mRNA transcript quantification in archival samples using multiplexed, color-coded probes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

A framework for variation discovery and genotyping using next-generation DNA sequencing data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

FIMO: scanning for occurrences of a given motif

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Integrative genomics viewer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Control-free calling of copy number alterations in deep-sequencing data using GC-content normalization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Cell signaling by receptor tyrosine kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Mutation-independent anaplastic lymphoma kinase overexpression in poor prognosis neuroblastoma patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Circos: an information aesthetic for comparative genomics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

The Sequence Alignment/Map format and SAMtools

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Fast and accurate short read alignment with Burrows-Wheeler transform

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

TopHat: discovering splice junctions with RNA-Seq

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

AmiGO: online access to ontology and annotation data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Model-based analysis of ChIP-Seq (MACS)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Identification of ALK as a major familial neuroblastoma predisposition gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Direct multiplexed measurement of gene expression with color-coded probe pairs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Chromatin modifications and their function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Interferon gamma is required for activation-induced death of T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4807020

5 September 2018

Identifiers

DOI

10.1038/NATURE15258

1 reference

15 August 2017

1 reference

15 August 2017

1 reference