(Q36728807)

English

Brain regional correlation of amyloid-β with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-β accumulation

scientific article published on 31 January 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Brain regional correlation of amyloid-β with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-β accumulation (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Dennis W. Dickson

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ronald C. Petersen

2

object named as

Ronald C Petersen

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Mitsuru Shinohara

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Guojun Bu

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

publication date

31 January 2013

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Acta Neuropathologica

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

125

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

535-547

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612369

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Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612369

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Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.

1 reference

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Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis

1 reference

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1 reference

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Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex

1 reference

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Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex

1 reference

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Alzheimer's disease: synapses gone cold

1 reference

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FE65 proteins regulate NMDA receptor activation-induced amyloid precursor protein processing

1 reference

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Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo

1 reference

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Neuronal activity regulates the regional vulnerability to amyloid-β deposition

1 reference

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Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake

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Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease

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1 reference

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Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ ) deposition

1 reference

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Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking

1 reference

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APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

1 reference

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The secretases: enzymes with therapeutic potential in Alzheimer disease

1 reference

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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

1 reference

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Biomarkers of glial cell proliferation and differentiation in culture

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30 September 2017

Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme

1 reference

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30 September 2017

Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition

1 reference

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30 September 2017

Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study.

1 reference

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30 September 2017

Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

1 reference

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30 September 2017

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

1 reference

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Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice

1 reference

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30 September 2017

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

1 reference

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Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase

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Amyloid precursor protein trafficking, processing, and function

1 reference

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

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ApoE promotes the proteolytic degradation of Abeta

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Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees

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ApoE plasma levels and risk of cardiovascular mortality in old age

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Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory

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Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice.

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Neuropathologic changes in Alzheimer's disease

1 reference

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Trafficking of cell-surface beta-amyloid precursor protein: evidence that a sorting intermediate participates in synaptic vesicle recycling

1 reference

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1 reference

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Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease

1 reference

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Neuropathological stageing of Alzheimer-related changes

1 reference

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Identification of normal and pathological aging in prospectively studied nondemented elderly humans

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612369

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High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types

1 reference

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1 reference

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Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612369

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Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice.

1 reference

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1 reference

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5 September 2018

Metabolic regulation of brain Abeta by neprilysin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612369

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Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612369

5 September 2018

Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-013-1086-9

21 January 2018

Distribution and characterization of the serum lipoproteins and apoproteins in the mouse, Mus musculus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma lipoproteins in the golden Syrian hamster (Mesocricetus auratus): heterogeneity of apoB- and apoA-I-containing particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00401-013-1086-9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

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