(Q36732878)

English

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.

scientific article published on July 2004

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX. (English)

1 reference

Europe PubMed Central

16 August 2017

0 references

0 references

author name string

Milota Kaluzová

1

1 reference

Europe PubMed Central

16 August 2017

Stefan Kaluz

2

1 reference

Europe PubMed Central

16 August 2017

Michael I Lerman

3

1 reference

Europe PubMed Central

16 August 2017

Eric J Stanbridge

4

1 reference

Europe PubMed Central

16 August 2017

language of work or name

0 references

publication date

1 July 2004

1 reference

Europe PubMed Central

16 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

16 August 2017

24

1 reference

Europe PubMed Central

16 August 2017

5757-5766

1 reference

Europe PubMed Central

16 August 2017

13

1 reference

Europe PubMed Central

16 August 2017

The histological structure of some human lung cancers and the possible implications for radiotherapy

1 reference

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30 September 2017

Targeting HIF-1 for cancer therapy

1 reference

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Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor

1 reference

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30 September 2017

Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function

1 reference

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30 September 2017

Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy

1 reference

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GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.

1 reference

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Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53.

1 reference

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Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase

1 reference

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Hypoxia--a key regulatory factor in tumour growth

1 reference

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30 September 2017

Hypoxia links ATR and p53 through replication arrest

1 reference

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30 September 2017

Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways

1 reference

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Characterization of the MN/CA 9 promoter proximal region: a role for specificity protein (SP) and activator protein 1 (AP1) factors

1 reference

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30 September 2017

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

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30 September 2017

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

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30 September 2017

Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast

1 reference

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30 September 2017

Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480909

30 September 2017

Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.

1 reference

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30 September 2017

Hypoxia-inducible expression of tumor-associated carbonic anhydrases

1 reference

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30 September 2017

Surfing the p53 network

1 reference

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30 September 2017

Stress signals utilize multiple pathways to stabilize p53

1 reference

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Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

1 reference

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

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Phase I/II radioimmunotherapy trial with iodine-131-labeled monoclonal antibody G250 in metastatic renal cell carcinoma

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30 September 2017

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

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MDM-2 oncoprotein overexpression, p53 gene mutation, and VEGF up-regulation in angiosarcomas

1 reference

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30 September 2017

Up-regulation of p53 by antisense expression of HPV18 E6 oncogene does not influence the level of MN/CA IX tumor-associated protein in HeLa cervical carcinoma cells.

1 reference

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Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes

1 reference

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The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480909

30 September 2017

Regulation of p53 stability by Mdm2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480909

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An essential role for p300/CBP in the cellular response to hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480909

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

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Expression of MaTu-MN protein in human tumor cultures and in clinical specimens

1 reference

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30 September 2017

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480909

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p53 mutations in human cancers

1 reference

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30 September 2017

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

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30 September 2017

P53 tumour suppressor modulates transcription of the TATA-less gene coding for the tumour-associated carbonic anhydrase MN/CA IX in MaTu cells.

1 reference

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Targeting of adenovirus to human renal cell carcinoma cells

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5 September 2018

Hypoxia attenuates the p53 response to cellular damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=480909

5 September 2018

Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer

1 reference

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

1 reference

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Generation of bidirectional hypoxia/HIF-responsive expression vectors to target gene expression to hypoxic cells

1 reference

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Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer

1 reference

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5 September 2018

Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix

1 reference

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p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

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based on heuristic

inferred from PubMed ID database lookup

p53 does not repress hypoxia-induced transcription of the vascular endothelial growth factor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of the MN/CA 9 gene coding for the tumor-associated carbonic anhydrase IX. Identification and characterization of a proximal silencer element

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

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based on heuristic

inferred from PubMed ID database lookup

Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammary carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

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based on heuristic

inferred from PubMed ID database lookup

Mycoplasma detection-an obligation to scientific accuracy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15199132

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.24.13.5757-5766.2004

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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