(Q36734151)

English

Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: possible role in antigen-driven reactions in the absence of germinal centers

scientific article published on November 1998

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: possible role in antigen-driven reactions in the absence of germinal centers (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Martin F Flajnik

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

M Diaz

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

A S Greenberg

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

1 November 1998

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

95

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

24

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

14343-14348

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Structural analysis of the nurse shark (new) antigen receptor (NAR): molecular convergence of NAR and unusual mammalian immunoglobulins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Structural insights into the evolution of an antibody combining site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Somatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglobulin heavy chain diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

The immunoglobulin genes of fish.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Production of 19S IgM antibodies with restricted heterogeneity from sharks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Genomic organization and sequences of immunoglobulin light chain genes in a primitive vertebrate suggest coevolution of immunoglobulin gene organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Intraclonal generation of antibody mutants in germinal centres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

The physiology of germinal centers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Positive darwinian selection observed at the variable-region genes of immunoglobulins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

30 September 2017

Evolution of somatic hypermutation and gene conversion in adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

Oligoclonal development of B cells bearing discrete Ig chains in chicken single germinal centers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

Lack of heterogeneity in anti-hapten antibodies of a phylogenetically primitive shark

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

A single rearrangement event generates most of the chicken immunoglobulin light chain diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

Major reorganization of immunoglobulin VH segmental elements during vertebrate evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

What limits affinity maturation of antibodies in Xenopus--the rate of somatic mutation or the ability to select mutants?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24375

28 June 2018

Coevolution of immunoglobulin heavy- and light-chain variable-region gene families

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Mismatch repair co-opted by hypermutation.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Antibody diversity in lower vertebrates—why is it so restricted?

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

A single VH family and long CDR3s are the targets for hypermutation in bovine immunoglobulin heavy chains

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Somatic hyperconversion diversifies the single Vh gene of the chicken with a high incidence in the D region

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Temperature and cellular regulation of spontaneous cytotoxicity in the shark

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Canonical VH CDR1 nucleotide sequences are conserved in all jawed vertebrates

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14343

21 January 2018

Divergent evolution and evolution by the birth-and-death process in the immunoglobulin VH gene family

1 reference

https://pubmed.ncbi.nlm.nih.gov/9826702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversification of rabbit VH genes by gene-conversion-like and hypermutation mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9826702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.95.24.14343

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1998PNAS...9514343D

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

0 references

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