(Q36734488)

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Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization

scientific article published on 9 November 2015

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Europe PubMed Central

PMC publication ID

16 August 2017

Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization (English)

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Europe PubMed Central

PMC publication ID

16 August 2017

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7 June 2020

9

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7 June 2020

author name string

Brittany Haynes

1

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7 June 2020

Fangchao Liu

3

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7 June 2020

Jing Li

4

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7 June 2020

Sarah Petit

5

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7 June 2020

Hend Kothayer

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7 June 2020

Xun Bao

7

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7 June 2020

Andrew D Westwell

8

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7 June 2020

Malathy P V Shekhar

10

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7 June 2020

publication date

9 November 2015

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16 August 2017

Nanomedicine: Nanotechnology, Biology and Medicine

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7 June 2020

12

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7 June 2020

3

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7 June 2020

745-757

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7 June 2020

Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy

1 reference

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30 September 2017

Novel inhibitors of Rad6 ubiquitin conjugating enzyme: design, synthesis, identification, and functional characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Therapeutic platforms based on gold nanoparticles and their covalent conjugates with drug molecules.

1 reference

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30 September 2017

Gold nanoparticles induce autophagosome accumulation through size-dependent nanoparticle uptake and lysosome impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Triple negative breast cancer cell lines: one tool in the search for better treatment of triple negative breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Protein transduction domain delivery of therapeutic macromolecules

1 reference

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30 September 2017

Virus-inspired design principles of nanoparticle-based bioagents

1 reference

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30 September 2017

Methods in mammalian autophagy research

1 reference

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30 September 2017

Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate

1 reference

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30 September 2017

Size-Dependent Endocytosis of Nanoparticles

1 reference

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30 September 2017

In vitro ultramorphological assessment of apoptosis induced by zerumbone on (HeLa).

1 reference

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30 September 2017

Nanoscintillators for microscopic diagnostics of biological and medical objects and medical therapy.

1 reference

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30 September 2017

PEGylated gold nanoparticles conjugated to monoclonal F19 antibodies as targeted labeling agents for human pancreatic carcinoma tissue

1 reference

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30 September 2017

Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell death

1 reference

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30 September 2017

Surfactant-polymer nanoparticles enhance the effectiveness of anticancer photodynamic therapy

1 reference

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30 September 2017

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

1 reference

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30 September 2017

Rad6B is a positive regulator of beta-catenin stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Mechanics of receptor-mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

RAD6B overexpression confers chemoresistance: RAD6 expression during cell cycle and its redistribution to chromatin during DNA damage-induced response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited

1 reference

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30 September 2017

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

1 reference

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30 September 2017

Poly(ADP-ribosylation) and apoptosis.

1 reference

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30 September 2017

Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis

1 reference

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30 September 2017

Mutagenesis in Saccharomyces cerevisiae.

1 reference

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30 September 2017

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809765

30 September 2017

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6

1 reference

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30 September 2017

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31

1 reference

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30 September 2017

Variable nanoparticle-cell adhesion strength regulates cellular uptake.

1 reference

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28 June 2018

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28 June 2018

Apoptosis: identification of dying cells

1 reference

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28 June 2018

A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

1 reference

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28 June 2018

Stable ester conjugate between the Saccharomyces cerevisiae RAD6 protein and ubiquitin has no biological activity

1 reference

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28 June 2018

Utility of DNA postreplication repair protein Rad6B in neoadjuvant chemotherapy response

1 reference

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5 September 2018

Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction

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Turkevich Method for Gold Nanoparticle Synthesis Revisited

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20 October 2018

Identifiers

10.1016/J.NANO.2015.10.010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26563438%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26563438%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26563438%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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