(Q36736035)

16 August 2017

The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21(BAX) expression (English)

1 reference

16 August 2017

H K Shu

1

1 reference

16 August 2017

M M Kim

2

1 reference

16 August 2017

P Chen

3

1 reference

16 August 2017

F Furman

4

1 reference

16 August 2017

C M Julin

5

1 reference

16 August 2017

M A Israel

6

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 November 1998

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

1 reference

16 August 2017

95

1 reference

16 August 2017

24

1 reference

16 August 2017

14453-14458

1 reference

BCL-2 family: regulators of cell death

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

P53-independent apoptosis: a mechanism of radiation-induced cell death of glioblastoma cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Cytogenetic damage and the radiation-induced G1-phase checkpoint

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Cell cycle synchrony unmasks the influence of p53 function on radiosensitivity of human glioblastoma cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

p53 is required for radiation-induced apoptosis in mouse thymocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

WAF1, a potential mediator of p53 tumor suppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

29 September 2017

The bcl-2 gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Radiation therapy of brain tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

The apoptosis-associated gamma-ray response of BCL-X(L) depends on normal p53 function.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

p53 protein accumulation and gene mutations in human glioma cell lines

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Identification of a p53-dependent negative response element in the bcl-2 gene

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Posterior fossa medulloblastoma in childhood: treatment results and a proposal for a new staging system.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Nitrogen mustard, vincristine, procarbazine, and prednisone as adjuvant chemotherapy in the treatment of medulloblastoma. A Pediatric Oncology Group study

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Low-dose craniospinal radiation therapy for medulloblastoma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Evidence for a 17p tumor related locus distinct from p53 in pediatric primitive neuroectodermal tumors.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Expression of the p53 protein in a spectrum of astrocytic tumours

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Infrequent p53 gene mutations in medulloblastomas.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

Constitutional p53 mutations associated with brain tumors in young adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

p53-dependent G1 arrest and p53-independent apoptosis influence the radiobiologic response of glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

Prognostic implications of p53 overexpression in supratentorial astrocytic tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Alterations of the TP53 gene in human gliomas.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24394

Frequency of p53 tumor suppressor gene mutations in human primary brain tumors

5 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.24.14453

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9826721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p53 mediated apoptosis in HeLa cells: transcription dependent and independent mechanisms

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9826721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inactivation of p53 is associated with decreased levels of radiation-induced apoptosis in medulloblastoma cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9826721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.95.24.14453

1 reference

16 August 2017

0 references

1 reference

16 August 2017

1 reference