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Low-fidelity DNA synthesis by human DNA polymerase theta.
scientific article published on 24 May 2008
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PMCID
2441791
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title
Low-fidelity DNA synthesis by human DNA polymerase theta
(English)
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Europe PubMed Central
PMCID
2441791
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7 January 2020
author
Richard D. Wood
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3
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2441791
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7 January 2020
Igor B. Rogozin
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4
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2441791
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7 January 2020
Thomas A Kunkel
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5
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2441791
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7 January 2020
Mercedes E Arana
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Mercedes E Arana
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2441791
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Mineaki Seki
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2
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2441791
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English
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publication date
24 May 2008
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2441791
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7 January 2020
published in
Nucleic Acids Research
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2441791
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7 January 2020
volume
36
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7 January 2020
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3847-3856
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7 January 2020
issue
11
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2441791
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Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification
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The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm
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DNA polymerase theta is preferentially expressed in lymphoid tissues and upregulated in human cancers
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DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.
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POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308
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29 September 2017
DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
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Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase
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29 September 2017
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit
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29 September 2017
Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday
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29 September 2017
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29 September 2017
High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase
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The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.
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29 September 2017
UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB.
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A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity.
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Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.
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5 September 2018
Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts
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5 September 2018
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5 September 2018
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes
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12 December 2020
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Replication of template-primers containing propanodeoxyguanosine by DNA polymerase beta. Induction of base pair substitution and frameshift mutations by template slippage and deoxynucleoside triphosphate stabilization
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12 December 2020
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DNA replication errors produced by the replicative apparatus of Escherichia coli.
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12 December 2020
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Mechanism of HIV-1 reverse transcriptase. Termination of processive synthesis on a natural DNA template is influenced by the sequence of the template-primer stem
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12 December 2020
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Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase
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12 December 2020
based on heuristic
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Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
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https://pubmed.ncbi.nlm.nih.gov/18503084
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12 December 2020
based on heuristic
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Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli
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The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit
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12 December 2020
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Identifiers
DOI
10.1093/NAR/GKN310
1 reference
stated in
Europe PubMed Central
PMCID
2441791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18503084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
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release_2s4os3ir5jgsff5tdch4h4d2vi
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24 November 2022
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mapped directly with Wikidata item
PMCID
2441791
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Europe PubMed Central
PMCID
2441791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18503084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PubMed ID
18503084
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Europe PubMed Central
PMCID
2441791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18503084%20AND%20SRC:MED&resulttype=core&format=json
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7 January 2020
ResearchGate publication ID
5347380
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