(Q36742268)

English

Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies

scientific article published on 15 February 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

solution structure

1 reference

based on heuristic

inferred from title

object named as

Shannon L Meeks

6

0 references

author name string

Justin D Walter

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Rachel A Werther

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Maria S Polozova

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Julie Pohlman

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

John F Healey

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Pete Lollar

7

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

P Clint Spiegel

8

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

15 February 2013

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

288

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

14

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

9905-9914

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Structural characterization of proteins and complexes using small-angle X-ray solution scattering.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Non-classical anti-factor VIII C2 domain antibodies are pathogenic in a murine in vivo bleeding model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Nonclassical anti-C2 domain antibodies are present in patients with factor VIII inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Acquired factor VIII inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

The tertiary structure and domain organization of coagulation factor VIII

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Structural transitions and thermodynamics of a glycine-dependent riboswitch from Vibrio cholerae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Determination of domain structure of proteins from X-ray solution scattering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

The future of plasma-derived clotting factor concentrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Structure of the C2 domain of human factor VIII at 1.5 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Incidence of inhibitors in haemophilia A patients--a review of recent studies of recombinant and plasma-derived factor VIII concentrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

The life cycle of coagulation factor VIII in view of its structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Mechanism and kinetics of factor VIII inactivation: study with an IgG4 monoclonal antibody derived from a hemophilia A patient with inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Reduced surface: an efficient way to compute molecular surfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Molecular cloning of a cDNA encoding human antihaemophilic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

29 September 2017

Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

28 June 2018

Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

28 June 2018

A multicenter study of recombinant factor VIII (recombinate): safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. The Recombinate Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

28 June 2018

Characterization of the human factor VIII gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

28 June 2018

The principal results of the International Immune Tolerance Study: a randomized dose comparison

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Antibody-based HIV-1 vaccines: recent developments and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Disruption of protein-membrane binding and identification of small-molecule inhibitors of coagulation factor VIII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

The safety and efficacy of B-domain deleted recombinant factor VIII concentrate in patients with severe haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Inhibitor development in previously untreated patients with hemophilia A: a prospective long-term follow-up comparing plasma-derived and recombinant products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Purity of factor VIII product and incidence of inhibitors in previously untreated patients with haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

The inhibitor antibody response is more complex in hemophilia A patients than in most nonhemophiliacs with factor VIII autoantibodies. Recombinate and Kogenate Study Groups.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Common inhibitory effects of human anti-C2 domain inhibitor alloantibodies on factor VIII binding to von Willebrand factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

Interaction of factor VIII-von Willebrand Factor with phospholipid vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617290

5 September 2018

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.424564

21 January 2018

PRIMUS: a Windows PC-based system for small-angle scattering data analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.424564

21 January 2018

UsingSitusfor the registration of protein structures with low-resolution bead models from X-ray solution scattering

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.424564

21 January 2018

Role of factor VIII C2 domain in factor VIII binding to factor Xa

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factor VIII C2 domain contains the thrombin-binding site responsible for thrombin-catalyzed cleavage at Arg1689

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit structure of thrombin-activated porcine factor VIII

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative binding of two antibodies to independent antigens by an Fc-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of factor VIII coagulant activity by two different types of human antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of phospholipid and factor VIIIa in the activation of bovine factor X

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human factor VIII procoagulant activity and phospholipid interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for the C2 domain of factor VIII in binding to von Willebrand factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanism for inhibition of factor VIII binding to phospholipid by von Willebrand factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and molecular aspects of the coagulation cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.424564

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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